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Perforin inhibition protects from lethal endothelial damage during fulminant viral hepatitis.
Welz, M; Eickhoff, S; Abdullah, Z; Trebicka, J; Gartlan, K H; Spicer, J A; Demetris, A J; Akhlaghi, H; Anton, M; Manske, K; Zehn, D; Nieswandt, B; Kurts, C; Trapani, J A; Knolle, P; Wohlleber, D; Kastenmüller, W.
Afiliação
  • Welz M; Institute of Experimental Immunology, University Hospital, University of Bonn, 53127, Bonn, Germany.
  • Eickhoff S; Institute of Experimental Immunology, University Hospital, University of Bonn, 53127, Bonn, Germany.
  • Abdullah Z; Institute of Experimental Immunology, University Hospital, University of Bonn, 53127, Bonn, Germany.
  • Trebicka J; Department of Internal Medicine I, University of Bonn, Bonn, 53127, Germany.
  • Gartlan KH; European Foundation for the Study of Chronic Liver Failure, Barcelona, 08021, Spain.
  • Spicer JA; QIMR Berghofer Medical Research Institute, 300 Herston Road QLD, Herston, 4006, Australia.
  • Demetris AJ; Auckland Cancer Society Research Centre, University of Auckland, Auckland, 92019, New Zealand.
  • Akhlaghi H; Department of Pathology, University of Pittsburgh, Pittsburgh, 15213, PA, USA.
  • Anton M; Peter MacCallum Cancer Centre, Melbourne, 3000, VIC, Australia.
  • Manske K; Institute of Molecular Immunology and Experimental Oncology, Klinikum rechts der Isar, Technical University of Munich, München, 81675, Germany.
  • Zehn D; Institute of Molecular Immunology and Experimental Oncology, Klinikum rechts der Isar, Technical University of Munich, München, 81675, Germany.
  • Nieswandt B; Division of Animal Physiology and Immunology, School of Life Sciences Weihenstephan, Technical University of Munich, Weihenstephaner Berg 3, Freising, 85354, Germany.
  • Kurts C; Institute of Experimental Biomedicine I, University of Wuerzburg, Wuerzburg, 97078, Germany.
  • Trapani JA; Institute of Experimental Immunology, University Hospital, University of Bonn, 53127, Bonn, Germany.
  • Knolle P; Peter MacCallum Cancer Centre, Melbourne, 3000, VIC, Australia.
  • Wohlleber D; Institute of Molecular Immunology and Experimental Oncology, Klinikum rechts der Isar, Technical University of Munich, München, 81675, Germany. percy.knolle@tum.de.
  • Kastenmüller W; Institute of Molecular Immunology and Experimental Oncology, Klinikum rechts der Isar, Technical University of Munich, München, 81675, Germany.
Nat Commun ; 9(1): 4805, 2018 11 15.
Article em En | MEDLINE | ID: mdl-30442932

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sulfonamidas / Substâncias Protetoras / Células Endoteliais / Proteínas Citotóxicas Formadoras de Poros / Hepatite Viral Animal / Fígado Tipo de estudo: Prognostic_studies Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Alemanha País de publicação: Reino Unido

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Sulfonamidas / Substâncias Protetoras / Células Endoteliais / Proteínas Citotóxicas Formadoras de Poros / Hepatite Viral Animal / Fígado Tipo de estudo: Prognostic_studies Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Alemanha País de publicação: Reino Unido