Neuroprotective effects of triterpenoid saponins from Medicago sativa L. against H<sub>2</sub>O<sub>2</sub>-induced oxidative stress in SH-SY5Y cells.

Liu, Xue-Gui; Sun, Yu-Qiu; Bian, Jun; Han, Ting; Yue, Dan-Dan; Li, Dan-Qi; Gao, Pin-Yi

Neuroprotective effects of triterpenoid saponins from Medicago sativa L. against H₂O₂-induced oxidative stress in SH-SY5Y cells.

Liu, Xue-Gui; Sun, Yu-Qiu; Bian, Jun; Han, Ting; Yue, Dan-Dan; Li, Dan-Qi; Gao, Pin-Yi.

Afiliação

Liu XG; College of Pharmaceutical and Biological Engineering, Shenyang University of Chemical Technology, Shenyang, Liaoning 110142, People's Republic of China; Institute of Functional Molecules, Shenyang University of Chemical Technology, Shenyang, Liaoning 110142, People's Republic of China.
Sun YQ; College of Pharmaceutical and Biological Engineering, Shenyang University of Chemical Technology, Shenyang, Liaoning 110142, People's Republic of China.
Bian J; College of Pharmaceutical and Biological Engineering, Shenyang University of Chemical Technology, Shenyang, Liaoning 110142, People's Republic of China.
Han T; College of Pharmaceutical and Biological Engineering, Shenyang University of Chemical Technology, Shenyang, Liaoning 110142, People's Republic of China.
Yue DD; College of Pharmaceutical and Biological Engineering, Shenyang University of Chemical Technology, Shenyang, Liaoning 110142, People's Republic of China.
Li DQ; College of Pharmaceutical and Biological Engineering, Shenyang University of Chemical Technology, Shenyang, Liaoning 110142, People's Republic of China; Institute of Functional Molecules, Shenyang University of Chemical Technology, Shenyang, Liaoning 110142, People's Republic of China. Electronic ad
Gao PY; College of Pharmaceutical and Biological Engineering, Shenyang University of Chemical Technology, Shenyang, Liaoning 110142, People's Republic of China; Institute of Functional Molecules, Shenyang University of Chemical Technology, Shenyang, Liaoning 110142, People's Republic of China. Electronic ad

Bioorg Chem ; 83: 468-476, 2019 03.

Article em En | MEDLINE | ID: mdl-30448725

Assuntos

Medicago sativa/química; Fármacos Neuroprotetores/farmacologia; Saponinas/farmacologia; Triterpenos/farmacologia; Linhagem Celular Tumoral; Sobrevivência Celular/efeitos dos fármacos; Cromanos/farmacologia; Humanos; Peróxido de Hidrogênio/farmacologia; Fármacos Neuroprotetores/química; Fármacos Neuroprotetores/isolamento & purificação; Estresse Oxidativo/efeitos dos fármacos; Saponinas/química; Saponinas/isolamento & purificação; Triterpenos/química; Triterpenos/isolamento & purificação

Palavras-chave

Medicago sativa L.; Neuroprotective effects; SH-SY5Y cells; Triterpenoid saponins

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Saponinas / Triterpenos / Fármacos Neuroprotetores / Medicago sativa Limite: Humans Idioma: En Revista: Bioorg Chem Ano de publicação: 2019 Tipo de documento: Article País de publicação: Estados Unidos

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