Cluster of Differentiation 46 Is the Major Receptor in Human Blood-Brain Barrier Endothelial Cells for Uptake of Exosomes Derived from Brain-Metastatic Melanoma Cells (SK-Mel-28).

Kuroda, Hiroki; Tachikawa, Masanori; Yagi, Yuta; Umetsu, Mina; Nurdin, Armania; Miyauchi, Eisuke; Watanabe, Michitoshi; Uchida, Yasuo; Terasaki, Tetsuya

Kuroda, Hiroki; Tachikawa, Masanori; Yagi, Yuta; Umetsu, Mina; Nurdin, Armania; Miyauchi, Eisuke; Watanabe, Michitoshi; Uchida, Yasuo; Terasaki, Tetsuya.

Afiliação

Kuroda H; Division of Membrane Transport and Drug Targeting, Graduate School of Pharmaceutical Sciences , Tohoku University , Sendai 980-8578 , Japan.
Tachikawa M; Division of Membrane Transport and Drug Targeting, Graduate School of Pharmaceutical Sciences , Tohoku University , Sendai 980-8578 , Japan.
Yagi Y; Division of Membrane Transport and Drug Targeting, Graduate School of Pharmaceutical Sciences , Tohoku University , Sendai 980-8578 , Japan.
Umetsu M; Division of Membrane Transport and Drug Targeting, Graduate School of Pharmaceutical Sciences , Tohoku University , Sendai 980-8578 , Japan.
Nurdin A; Division of Membrane Transport and Drug Targeting, Graduate School of Pharmaceutical Sciences , Tohoku University , Sendai 980-8578 , Japan.
Miyauchi E; Division of Membrane Transport and Drug Targeting, Graduate School of Pharmaceutical Sciences , Tohoku University , Sendai 980-8578 , Japan.
Watanabe M; Division of Membrane Transport and Drug Targeting, Graduate School of Pharmaceutical Sciences , Tohoku University , Sendai 980-8578 , Japan.
Uchida Y; Division of Membrane Transport and Drug Targeting, Graduate School of Pharmaceutical Sciences , Tohoku University , Sendai 980-8578 , Japan.
Terasaki T; Division of Membrane Transport and Drug Targeting, Graduate School of Pharmaceutical Sciences , Tohoku University , Sendai 980-8578 , Japan.

Mol Pharm ; 16(1): 292-304, 2019 01 07.

Article em En | MEDLINE | ID: mdl-30452273

Assuntos

Encéfalo/metabolismo; Exossomos/metabolismo; Proteômica/métodos; Transporte Biológico/fisiologia; Barreira Hematoencefálica/metabolismo; Linhagem Celular Tumoral; Células Endoteliais/metabolismo; Humanos; Melanoma/metabolismo; Proteína Cofatora de Membrana/metabolismo; RNA Interferente Pequeno; Receptores Virais/metabolismo

Palavras-chave

CD46; brain-metastatic cancer; comprehensive proteomics SWATH; cross-linking; exosomes; human blood−brain barrier; virus receptor

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Encéfalo / Proteômica / Exossomos Tipo de estudo: Prognostic_studies Limite: Humans Idioma: En Revista: Mol Pharm Assunto da revista: BIOLOGIA MOLECULAR / FARMACIA / FARMACOLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Japão País de publicação: Estados Unidos

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