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Exploring the reason for increased activity of SHP2 caused by D61Y mutation through molecular dynamics.
Wang, Rui-Rui; Ma, Ying; Du, Shan; Li, Wei-Ya; Sun, Ying-Zhan; Zhou, Hui; Wang, Run-Ling.
Afiliação
  • Wang RR; Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics (Theranostics), School of Pharmacy, Tianjin Medical University, Tianjin, 300070, China.
  • Ma Y; Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics (Theranostics), School of Pharmacy, Tianjin Medical University, Tianjin, 300070, China.
  • Du S; Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics (Theranostics), School of Pharmacy, Tianjin Medical University, Tianjin, 300070, China.
  • Li WY; Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics (Theranostics), School of Pharmacy, Tianjin Medical University, Tianjin, 300070, China.
  • Sun YZ; Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics (Theranostics), School of Pharmacy, Tianjin Medical University, Tianjin, 300070, China.
  • Zhou H; Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics (Theranostics), School of Pharmacy, Tianjin Medical University, Tianjin, 300070, China.
  • Wang RL; Tianjin Key Laboratory on Technologies Enabling Development of Clinical Therapeutics and Diagnostics (Theranostics), School of Pharmacy, Tianjin Medical University, Tianjin, 300070, China. Electronic address: wangrunling@tmu.edu.cn.
Comput Biol Chem ; 78: 133-143, 2019 Feb.
Article em En | MEDLINE | ID: mdl-30508783
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteína Tirosina Fosfatase não Receptora Tipo 11 / Simulação de Dinâmica Molecular / Mutação Limite: Humans Idioma: En Revista: Comput Biol Chem Assunto da revista: BIOLOGIA / INFORMATICA MEDICA / QUIMICA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China País de publicação: Reino Unido
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteína Tirosina Fosfatase não Receptora Tipo 11 / Simulação de Dinâmica Molecular / Mutação Limite: Humans Idioma: En Revista: Comput Biol Chem Assunto da revista: BIOLOGIA / INFORMATICA MEDICA / QUIMICA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China País de publicação: Reino Unido