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Targeting the BRD4/FOXO3a/CDK6 axis sensitizes AKT inhibition in luminal breast cancer.
Liu, Jingyi; Duan, Zhibing; Guo, Weijie; Zeng, Lei; Wu, Yadi; Chen, Yule; Tai, Fang; Wang, Yifan; Lin, Yiwei; Zhang, Qiang; He, Yanling; Deng, Jiong; Stewart, Rachel L; Wang, Chi; Lin, Pengnian Charles; Ghaffari, Saghi; Evers, B Mark; Liu, Suling; Zhou, Ming-Ming; Zhou, Binhua P; Shi, Jian.
Afiliação
  • Liu J; Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY, 40506, USA.
  • Duan Z; Markey Cancer Center, University of Kentucky College of Medicine, Lexington, KY, 40506, USA.
  • Guo W; Center for Cancer Research, National Cancer Institute-Frederick, Frederick, MD, 21702, USA.
  • Zeng L; Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY, 40506, USA.
  • Wu Y; Markey Cancer Center, University of Kentucky College of Medicine, Lexington, KY, 40506, USA.
  • Chen Y; Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY, 40506, USA.
  • Tai F; Markey Cancer Center, University of Kentucky College of Medicine, Lexington, KY, 40506, USA.
  • Wang Y; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
  • Lin Y; Bethune Institute of Epigenetic Medicine, The First Hospital, Jilin University, Changchun, Jilin, 130021, China.
  • Zhang Q; Markey Cancer Center, University of Kentucky College of Medicine, Lexington, KY, 40506, USA.
  • He Y; Department of Molecular and Biomedical Pharmacology, University of Kentucky College of Medicine, Lexington, KY, 40506, USA.
  • Deng J; Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY, 40506, USA.
  • Stewart RL; Markey Cancer Center, University of Kentucky College of Medicine, Lexington, KY, 40506, USA.
  • Wang C; Department of Pathology, School of Basic Medical Sciences, Southern Medical University, Guangzhou, Guangdong, 510515, China.
  • Lin PC; Department of Pathology, Nanfang Hospital, Southern Medical University, Guangzhou, Guangdong, 510515, China.
  • Ghaffari S; Guangdong Provincial Key Laboratory of Molecular Tumor Pathology, Southern Medical University, Guangzhou, Guangdong, 510515, China.
  • Evers BM; Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY, 40506, USA.
  • Liu S; Markey Cancer Center, University of Kentucky College of Medicine, Lexington, KY, 40506, USA.
  • Zhou MM; Department of Molecular and Cellular Biochemistry, University of Kentucky College of Medicine, Lexington, KY, 40506, USA.
  • Zhou BP; Markey Cancer Center, University of Kentucky College of Medicine, Lexington, KY, 40506, USA.
  • Shi J; Department of Pharmacological Sciences, Icahn School of Medicine at Mount Sinai, New York, NY, 10029, USA.
Nat Commun ; 9(1): 5200, 2018 12 05.
Article em En | MEDLINE | ID: mdl-30518851
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Neoplasias da Mama / Proteínas Nucleares / Quinase 6 Dependente de Ciclina / Proteínas Proto-Oncogênicas c-akt / Proteína Forkhead Box O3 Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos
Texto completo
Adicionar na Minha BVS
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fatores de Transcrição / Neoplasias da Mama / Proteínas Nucleares / Quinase 6 Dependente de Ciclina / Proteínas Proto-Oncogênicas c-akt / Proteína Forkhead Box O3 Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Estados Unidos