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Microtubule-Targeting 7-Deazahypoxanthines Derived from Marine Alkaloid Rigidins: Exploration of the N3 and N9 Positions and Interaction with Multidrug-Resistance Proteins.
Dasari, Ramesh; Blauz, Andrzej; Medellin, Derek C; Kassim, Roaa M; Viera, Carlos; Santarosa, Maximo; van der Westhuyzen, Alet E; van Otterlo, Willem A L; Olivas, Taryn; Yildiz, Tugba; Betancourt, Tania; Shuster, Charles B; Rogelj, Snezna; Rychlik, Blazej; Hudnall, Todd; Frolova, Liliya V; Kornienko, Alexander.
Afiliação
  • Dasari R; Department of Chemistry and Biochemistry, Texas State University, San Marcos, TX, 78666, USA.
  • Blauz A; Cytometry Lab, Department of Molecular Biophysics, Faculty of Biology and Environmental Protection, University of Lódz, ul. Pomorska 141/143, 90-236, Lódz, Poland.
  • Medellin DC; Department of Chemistry and Biochemistry, Texas State University, San Marcos, TX, 78666, USA.
  • Kassim RM; Department of Biology, New Mexico State University, Las Cruces, NM, 88003, USA.
  • Viera C; Departments of Chemistry and Biology, New Mexico Tech, Socorro, NM, 87801, USA.
  • Santarosa M; Departments of Chemistry and Biology, New Mexico Tech, Socorro, NM, 87801, USA.
  • van der Westhuyzen AE; Department of Chemistry and Polymer Science, University of Stellenbosch, 7602, Stellenbosch, South Africa.
  • van Otterlo WAL; Department of Chemistry and Polymer Science, University of Stellenbosch, 7602, Stellenbosch, South Africa.
  • Olivas T; Department of Chemistry and Biochemistry, Texas State University, San Marcos, TX, 78666, USA.
  • Yildiz T; Materials Science and Engineering Program, Texas State University, San Marcos, TX, 78666, USA.
  • Betancourt T; Department of Chemistry and Biochemistry, Texas State University, San Marcos, TX, 78666, USA.
  • Shuster CB; Materials Science and Engineering Program, Texas State University, San Marcos, TX, 78666, USA.
  • Rogelj S; Department of Biology, New Mexico State University, Las Cruces, NM, 88003, USA.
  • Rychlik B; Departments of Chemistry and Biology, New Mexico Tech, Socorro, NM, 87801, USA.
  • Hudnall T; Cytometry Lab, Department of Molecular Biophysics, Faculty of Biology and Environmental Protection, University of Lódz, ul. Pomorska 141/143, 90-236, Lódz, Poland.
  • Frolova LV; Department of Chemistry and Biochemistry, Texas State University, San Marcos, TX, 78666, USA.
  • Kornienko A; Departments of Chemistry and Biology, New Mexico Tech, Socorro, NM, 87801, USA.
ChemMedChem ; 14(3): 322-333, 2019 02 05.
Article em En | MEDLINE | ID: mdl-30562414
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirimidinas / Pirróis / Hipoxantina / Subfamília B de Transportador de Cassetes de Ligação de ATP / Alcaloides / Microtúbulos / Antineoplásicos Limite: Animals / Humans Idioma: En Revista: ChemMedChem Assunto da revista: FARMACOLOGIA / QUIMICA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Alemanha
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirimidinas / Pirróis / Hipoxantina / Subfamília B de Transportador de Cassetes de Ligação de ATP / Alcaloides / Microtúbulos / Antineoplásicos Limite: Animals / Humans Idioma: En Revista: ChemMedChem Assunto da revista: FARMACOLOGIA / QUIMICA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Alemanha