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Elevated pyrimidine dimer formation at distinct genomic bases underlies promoter mutation hotspots in UV-exposed cancers.
Elliott, Kerryn; Boström, Martin; Filges, Stefan; Lindberg, Markus; Van den Eynden, Jimmy; Ståhlberg, Anders; Clausen, Anders R; Larsson, Erik.
Afiliação
  • Elliott K; Department of Medical Biochemistry and Cell Biology, Institute of Biomedicine, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
  • Boström M; Department of Medical Biochemistry and Cell Biology, Institute of Biomedicine, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
  • Filges S; Sahlgrenska Cancer Center, Department of Pathology and Genetics, Institute of Biomedicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden.
  • Lindberg M; Wallenberg Centre for Molecular and Translational Medicine, University of Gothenburg, Sweden.
  • Van den Eynden J; Department of Clinical Pathology and Genetics, Sahlgrenska University Hospital, Gothenburg, Sweden.
  • Ståhlberg A; Department of Medical Biochemistry and Cell Biology, Institute of Biomedicine, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
  • Clausen AR; Department of Medical Biochemistry and Cell Biology, Institute of Biomedicine, The Sahlgrenska Academy, University of Gothenburg, Gothenburg, Sweden.
  • Larsson E; Sahlgrenska Cancer Center, Department of Pathology and Genetics, Institute of Biomedicine, Sahlgrenska Academy at University of Gothenburg, Gothenburg, Sweden.
PLoS Genet ; 14(12): e1007849, 2018 12.
Article em En | MEDLINE | ID: mdl-30586386
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dímeros de Pirimidina / Neoplasias Cutâneas / Raios Ultravioleta / Melanoma / Mutação / Neoplasias Induzidas por Radiação Limite: Humans Idioma: En Revista: PLoS Genet Assunto da revista: GENETICA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Suécia País de publicação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dímeros de Pirimidina / Neoplasias Cutâneas / Raios Ultravioleta / Melanoma / Mutação / Neoplasias Induzidas por Radiação Limite: Humans Idioma: En Revista: PLoS Genet Assunto da revista: GENETICA Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Suécia País de publicação: Estados Unidos