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UBQLN4 Represses Homologous Recombination and Is Overexpressed in Aggressive Tumors.
Jachimowicz, Ron D; Beleggia, Filippo; Isensee, Jörg; Velpula, Bhagya Bhavana; Goergens, Jonas; Bustos, Matias A; Doll, Markus A; Shenoy, Anjana; Checa-Rodriguez, Cintia; Wiederstein, Janica Lea; Baranes-Bachar, Keren; Bartenhagen, Christoph; Hertwig, Falk; Teper, Nizan; Nishi, Tomohiko; Schmitt, Anna; Distelmaier, Felix; Lüdecke, Hermann-Josef; Albrecht, Beate; Krüger, Marcus; Schumacher, Björn; Geiger, Tamar; Hoon, Dave S B; Huertas, Pablo; Fischer, Matthias; Hucho, Tim; Peifer, Martin; Ziv, Yael; Reinhardt, H Christian; Wieczorek, Dagmar; Shiloh, Yosef.
Afiliação
  • Jachimowicz RD; The David and Inez Myers Laboratory for Cancer Genetics, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel; Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel; Clinic I of Internal Medicine, Universit
  • Beleggia F; Clinic I of Internal Medicine, University Hospital Cologne, Cologne 50931, Germany; Institute of Human Genetics, Heinrich-Heine-University, Düsseldorf, Germany.
  • Isensee J; Department of Anesthesiology and Intensive Care Medicine, Experimental Anesthesiology and Pain Research, University Hospital Cologne, Cologne 50931, Germany.
  • Velpula BB; The David and Inez Myers Laboratory for Cancer Genetics, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel; Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel.
  • Goergens J; Clinic I of Internal Medicine, University Hospital Cologne, Cologne 50931, Germany.
  • Bustos MA; Department of Translational Molecular Medicine, Division of Molecular Oncology, John Wayne Cancer Institute at Providence Saint John's Health Center, Santa Monica, CA, USA.
  • Doll MA; Cologne Excellence Cluster on Cellular Stress Response in Aging-Associated Diseases, University of Cologne, Cologne, Germany; Institute for Genome Stability in Aging, Cologne, Germany.
  • Shenoy A; Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel.
  • Checa-Rodriguez C; Centro Andaluz de Biología Molecular y Medicina Regenerativa-CABIMER, Universidad de Sevilla-CSIC-Universidad Pablo de Olavide and Department of Genetics, University of Sevilla, Sevilla 41092, Spain.
  • Wiederstein JL; Cologne Excellence Cluster on Cellular Stress Response in Aging-Associated Diseases, University of Cologne, Cologne, Germany.
  • Baranes-Bachar K; The David and Inez Myers Laboratory for Cancer Genetics, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel; Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel.
  • Bartenhagen C; Department of Experimental Pediatric Oncology, University Hospital Cologne, Cologne, Germany; Center for Molecular Medicine Cologne, University of Cologne, Cologne, Germany.
  • Hertwig F; Department of Pediatric Oncology and Hematology, Charité, Berlin, Germany; German Cancer Consortium, Germany; Berlin Institute of Health, Germany.
  • Teper N; The David and Inez Myers Laboratory for Cancer Genetics, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel; Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel.
  • Nishi T; Department of Translational Molecular Medicine, Division of Molecular Oncology, John Wayne Cancer Institute at Providence Saint John's Health Center, Santa Monica, CA, USA.
  • Schmitt A; Clinic I of Internal Medicine, University Hospital Cologne, Cologne 50931, Germany.
  • Distelmaier F; Department of General Pediatrics, Neonatology and Pediatric Cardiology, University Hospital, Heinrich-Heine-University, Düsseldorf 40225, Germany.
  • Lüdecke HJ; Institute of Human Genetics, Heinrich-Heine-University, Düsseldorf, Germany; Institute of Human Genetics, University Clinic Duisburg-Essen, Essen, Germany.
  • Albrecht B; Institute of Human Genetics, University Clinic Duisburg-Essen, Essen, Germany.
  • Krüger M; Cologne Excellence Cluster on Cellular Stress Response in Aging-Associated Diseases, University of Cologne, Cologne, Germany; Center for Molecular Medicine Cologne, University of Cologne, Cologne, Germany.
  • Schumacher B; Cologne Excellence Cluster on Cellular Stress Response in Aging-Associated Diseases, University of Cologne, Cologne, Germany; Institute for Genome Stability in Aging, Cologne, Germany.
  • Geiger T; Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel.
  • Hoon DSB; Department of Translational Molecular Medicine, Division of Molecular Oncology, John Wayne Cancer Institute at Providence Saint John's Health Center, Santa Monica, CA, USA.
  • Huertas P; Centro Andaluz de Biología Molecular y Medicina Regenerativa-CABIMER, Universidad de Sevilla-CSIC-Universidad Pablo de Olavide and Department of Genetics, University of Sevilla, Sevilla 41092, Spain.
  • Fischer M; Department of Experimental Pediatric Oncology, University Hospital Cologne, Cologne, Germany; Center for Molecular Medicine Cologne, University of Cologne, Cologne, Germany.
  • Hucho T; Department of Anesthesiology and Intensive Care Medicine, Experimental Anesthesiology and Pain Research, University Hospital Cologne, Cologne 50931, Germany.
  • Peifer M; Center for Molecular Medicine Cologne, University of Cologne, Cologne, Germany; Department of Translational Genomics, University of Cologne, Cologne, Germany.
  • Ziv Y; The David and Inez Myers Laboratory for Cancer Genetics, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel; Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel. Electronic address: yaelz@post.tau.ac.il
  • Reinhardt HC; Clinic I of Internal Medicine, University Hospital Cologne, Cologne 50931, Germany; Cologne Excellence Cluster on Cellular Stress Response in Aging-Associated Diseases, University of Cologne, Cologne, Germany; Center for Molecular Medicine Cologne, University of Cologne, Cologne, Germany. Electronic
  • Wieczorek D; Institute of Human Genetics, Heinrich-Heine-University, Düsseldorf, Germany; Institute of Human Genetics, University Clinic Duisburg-Essen, Essen, Germany. Electronic address: dagmar.wieczorek@hhu.de.
  • Shiloh Y; The David and Inez Myers Laboratory for Cancer Genetics, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel; Department of Human Molecular Genetics and Biochemistry, Sackler School of Medicine, Tel Aviv University, Tel Aviv 69978, Israel. Electronic address: yossih@post.tau.ac.i
Cell ; 176(3): 505-519.e22, 2019 01 24.
Article em En | MEDLINE | ID: mdl-30612738

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Nucleares / Proteínas de Transporte Tipo de estudo: Prognostic_studies Limite: Female / Humans / Male Idioma: En Revista: Cell Ano de publicação: 2019 Tipo de documento: Article País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Proteínas Nucleares / Proteínas de Transporte Tipo de estudo: Prognostic_studies Limite: Female / Humans / Male Idioma: En Revista: Cell Ano de publicação: 2019 Tipo de documento: Article País de publicação: Estados Unidos