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Failure to eliminate a phosphorylated glucose analog leads to neutropenia in patients with G6PT and G6PC3 deficiency.
Veiga-da-Cunha, Maria; Chevalier, Nathalie; Stephenne, Xavier; Defour, Jean-Philippe; Paczia, Nicole; Ferster, Alina; Achouri, Younes; Dewulf, Joseph P; Linster, Carole L; Bommer, Guido T; Van Schaftingen, Emile.
Afiliação
  • Veiga-da-Cunha M; Walloon Excellence in Lifesciences and Biotechnology, B-1200 Brussels, Belgium; maria.veiga@uclouvain.be emile.vanschaftingen@uclouvain.be.
  • Chevalier N; Groupe de Recherches Metaboliques, de Duve Institute, UCLouvain (Université Catholique de Louvain), B-1200 Brussels, Belgium.
  • Stephenne X; Walloon Excellence in Lifesciences and Biotechnology, B-1200 Brussels, Belgium.
  • Defour JP; Groupe de Recherches Metaboliques, de Duve Institute, UCLouvain (Université Catholique de Louvain), B-1200 Brussels, Belgium.
  • Paczia N; Service de Gastro-Entérologie et Hépatologie Pédiatrique, Cliniques Universitaires Saint-Luc, UCLouvain, B-1200 Brussels, Belgium.
  • Ferster A; Groupe de Recherches Metaboliques, de Duve Institute, UCLouvain (Université Catholique de Louvain), B-1200 Brussels, Belgium.
  • Achouri Y; Biologie Hématologique, Cliniques Universitaires Saint-Luc, UCLouvain, B-1200 Brussels, Belgium.
  • Dewulf JP; Luxembourg Centre for Systems Biomedicine, Université du Luxembourg, L-4367 Belvaux, Luxembourg.
  • Linster CL; Department of Hematology/Oncology, Hôpital Universitaire des Enfants Reine Fabiola, Université Libre de Bruxelles, B-1020 Brussels, Belgium.
  • Bommer GT; Groupe de Recherches Metaboliques, de Duve Institute, UCLouvain (Université Catholique de Louvain), B-1200 Brussels, Belgium.
  • Van Schaftingen E; Walloon Excellence in Lifesciences and Biotechnology, B-1200 Brussels, Belgium.
Proc Natl Acad Sci U S A ; 116(4): 1241-1250, 2019 01 22.
Article em En | MEDLINE | ID: mdl-30626647
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosforilação / Proteínas de Transporte de Monossacarídeos / Antiporters / Glucose-6-Fosfatase / Glucose / Neutropenia Limite: Animals / Female / Humans / Male Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2019 Tipo de documento: Article País de publicação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fosforilação / Proteínas de Transporte de Monossacarídeos / Antiporters / Glucose-6-Fosfatase / Glucose / Neutropenia Limite: Animals / Female / Humans / Male Idioma: En Revista: Proc Natl Acad Sci U S A Ano de publicação: 2019 Tipo de documento: Article País de publicação: Estados Unidos