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Whole genomes define concordance of matched primary, xenograft, and organoid models of pancreas cancer.
Gendoo, Deena M A; Denroche, Robert E; Zhang, Amy; Radulovich, Nikolina; Jang, Gun Ho; Lemire, Mathieu; Fischer, Sandra; Chadwick, Dianne; Lungu, Ilinca M; Ibrahimov, Emin; Cao, Ping-Jiang; Stein, Lincoln D; Wilson, Julie M; Bartlett, John M S; Tsao, Ming-Sound; Dhani, Neesha; Hedley, David; Gallinger, Steven; Haibe-Kains, Benjamin.
Afiliação
  • Gendoo DMA; Centre for Computational Biology, Institute of Cancer and Genomic Sciences, University of Birmingham, Birmingham, United Kingdom.
  • Denroche RE; School of Science and Technology, Nottingham Trent University, Nottingham, United Kingdom.
  • Zhang A; PanCuRx Translational Research Initiative, Ontario Institute of Cancer Research (OICR), Toronto, Ontario, Canada.
  • Radulovich N; PanCuRx Translational Research Initiative, Ontario Institute of Cancer Research (OICR), Toronto, Ontario, Canada.
  • Jang GH; Informatics and Bio-computing Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.
  • Lemire M; PanCuRx Translational Research Initiative, Ontario Institute of Cancer Research (OICR), Toronto, Ontario, Canada.
  • Fischer S; Informatics and Bio-computing Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.
  • Chadwick D; Princess Margaret Living Biobank Core, University Health Network, Toronto, Ontario, Canada.
  • Lungu IM; PanCuRx Translational Research Initiative, Ontario Institute of Cancer Research (OICR), Toronto, Ontario, Canada.
  • Ibrahimov E; Informatics and Bio-computing Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.
  • Cao PJ; Department of Statistical Science, University of Toronto, Toronto, Ontario, Canada.
  • Stein LD; PanCuRx Translational Research Initiative, Ontario Institute of Cancer Research (OICR), Toronto, Ontario, Canada.
  • Wilson JM; Department of Pathology, University Health Network, University of Toronto, Toronto, Ontario, Canada.
  • Bartlett JMS; UHN Program in BioSpecimen Sciences, Department of Pathology, University Health Network, Toronto, Ontario, Canada.
  • Tsao MS; Transformative Pathology, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.
  • Dhani N; Princess Margaret Living Biobank Core, University Health Network, Toronto, Ontario, Canada.
  • Hedley D; Division of Medical Oncology, Princess Margaret Cancer Centre, Toronto, Ontario, Canada.
  • Gallinger S; Informatics and Bio-computing Program, Ontario Institute for Cancer Research, Toronto, Ontario, Canada.
  • Haibe-Kains B; Molecular Genetics Department, University of Toronto, Toronto, Ontario, Canada.
PLoS Comput Biol ; 15(1): e1006596, 2019 01.
Article em En | MEDLINE | ID: mdl-30629588
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Genoma / Carcinoma Ductal Pancreático / Modelos Biológicos / Neoplasias Experimentais Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: PLoS Comput Biol Assunto da revista: BIOLOGIA / INFORMATICA MEDICA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Pancreáticas / Genoma / Carcinoma Ductal Pancreático / Modelos Biológicos / Neoplasias Experimentais Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: PLoS Comput Biol Assunto da revista: BIOLOGIA / INFORMATICA MEDICA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Estados Unidos