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[Clinical management of patients with hemophilia A in nephrology: Diagnostic and therapeutic challenges illustrated by the cases of 2 patients]. / Prise en charge néphrologique des patients hémophiles A : difficultés diagnostiques et thérapeutiques illustrées par le cas de 2 patients.
Fedi, Mathilde; Falaise, Céline; Lanot, Antoine; Von Kotze, Clarissa; Robert, Thomas; Piétri, Léa; Henri, Patrick; Delmotte, Nicolas; Botta, Danielle; Verhelst, David; Chambost, Hervé; Brunet, Philippe; Jourde-Chiche, Noémie.
Afiliação
  • Fedi M; Centre de néphrologie et transplantation rénale, hôpital de la conception, 147, boulevard Baille, Assistance publique-Hôpitaux de Marseille, 13005 Marseille, France.
  • Falaise C; Centre des maladies hémorragiques constitutionnelles, hôpital de la Timone, Assistance publique-Hôpitaux de Marseille, 13005 Marseille, France.
  • Lanot A; Service de néphrologie, dialyse et transplantation, CHU de Caen, 14000 Caen, France.
  • Von Kotze C; Centre de néphrologie et transplantation rénale, hôpital de la conception, 147, boulevard Baille, Assistance publique-Hôpitaux de Marseille, 13005 Marseille, France.
  • Robert T; Centre de néphrologie et transplantation rénale, hôpital de la conception, 147, boulevard Baille, Assistance publique-Hôpitaux de Marseille, 13005 Marseille, France.
  • Piétri L; Service d'endocrinologie, hôpital de la conception, 147, boulevard Baille, Assistance publique-Hôpitaux de Marseille, 13005 Marseille, France.
  • Henri P; Service de néphrologie, dialyse et transplantation, CHU de Caen, 14000 Caen, France.
  • Delmotte N; Pharmacie, hôpital de la conception, 147, boulevard Baille, Assistance publique-Hôpitaux de Marseille, 13005 Marseille, France.
  • Botta D; Service d'hépato-gastro-entérologie, hôpital de la Timone, Assistance publique-Hôpitaux de Marseille, 13005 Marseille, France.
  • Verhelst D; Service de néphrologie, centre hospitalier d'Avignon, 84000 Avignon, France.
  • Chambost H; Centre des maladies hémorragiques constitutionnelles, hôpital de la Timone, Assistance publique-Hôpitaux de Marseille, 13005 Marseille, France; Center for cardiovascular and nutrition research (C2VN), Inra 1260, Inserm 1263, Aix-Marseille Université, Campus Timone, 13005 Marseille, France.
  • Brunet P; Centre de néphrologie et transplantation rénale, hôpital de la conception, 147, boulevard Baille, Assistance publique-Hôpitaux de Marseille, 13005 Marseille, France; Center for cardiovascular and nutrition research (C2VN), Inra 1260, Inserm 1263, Aix-Marseille Université, Campus Timone, 13005 Marsei
  • Jourde-Chiche N; Centre de néphrologie et transplantation rénale, hôpital de la conception, 147, boulevard Baille, Assistance publique-Hôpitaux de Marseille, 13005 Marseille, France; Center for cardiovascular and nutrition research (C2VN), Inra 1260, Inserm 1263, Aix-Marseille Université, Campus Timone, 13005 Marsei
Nephrol Ther ; 15(2): 77-81, 2019 Apr.
Article em Fr | MEDLINE | ID: mdl-30660587
Hemophilia A is an X-linked genetic hemorrhagic disorder characterized by a factor VIII deficiency. The availability of secured substitution products has led to a dramatic improvement of life expectancy in hemophiliac patients. Nowadays, adult hemophiliac patients may develop Chronic Kidney Disease (CKD) resulting from age-related comorbidities (hypertension, obesity, diabetes). In addition, the high prevalence of viral infections in this population exposes patients to an increased risk of CKD. The risk of hemorrhage in hemophiliac patients is a challenge for their clinical management, both for diagnostic procedures (kidney biopsy in particular) and for renal replacement therapy (dialysis or renal transplantation) when it is needed. This work provides an update of the literature data concerning the management of hemophiliac patients in nephrology, illustrated by the cases of two patients.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Diálise Renal / Injúria Renal Aguda / Hemofilia A Tipo de estudo: Diagnostic_studies / Etiology_studies / Risk_factors_studies Limite: Humans / Male / Middle aged Idioma: Fr Revista: Nephrol Ther Assunto da revista: NEFROLOGIA / TERAPEUTICA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: França País de publicação: França

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Diálise Renal / Injúria Renal Aguda / Hemofilia A Tipo de estudo: Diagnostic_studies / Etiology_studies / Risk_factors_studies Limite: Humans / Male / Middle aged Idioma: Fr Revista: Nephrol Ther Assunto da revista: NEFROLOGIA / TERAPEUTICA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: França País de publicação: França