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Host-Guest Interactions between Candesartan and Its Prodrug Candesartan Cilexetil in Complex with 2-Hydroxypropyl-ß-cyclodextrin: On the Biological Potency for Angiotensin II Antagonism.
Ntountaniotis, Dimitrios; Andreadelis, Ioannis; Kellici, Tahsin F; Karageorgos, Vlasios; Leonis, Georgios; Christodoulou, Eirini; Kiriakidi, Sofia; Becker-Baldus, Johanna; Stylos, Evgenios K; Chatziathanasiadou, Maria V; Chatzigiannis, Christos M; Damalas, Dimitrios E; Aksoydan, Busecan; Javornik, Uros; Valsami, Georgia; Glaubitz, Clemens; Durdagi, Serdar; Thomaidis, Nikolaos S; Kolocouris, Antonios; Plavec, Janez; Tzakos, Andreas G; Liapakis, George; Mavromoustakos, Thomas.
Afiliação
  • Ntountaniotis D; Department of Chemistry, Laboratory of Organic Chemistry , National and Kapodistrian University of Athens , Panepistimioupolis, Zografou 15771 , Greece.
  • Andreadelis I; Department of Chemistry, Laboratory of Organic Chemistry , National and Kapodistrian University of Athens , Panepistimioupolis, Zografou 15771 , Greece.
  • Kellici TF; Department of Chemistry, Laboratory of Organic Chemistry , National and Kapodistrian University of Athens , Panepistimioupolis, Zografou 15771 , Greece.
  • Karageorgos V; Department of Pharmacology, School of Medicine , University of Crete , Heraklion, Crete 70013 , Greece.
  • Leonis G; Department of Chemistry, Laboratory of Organic Chemistry , National and Kapodistrian University of Athens , Panepistimioupolis, Zografou 15771 , Greece.
  • Christodoulou E; Department of Pharmacy, Laboratory of Pharmaceutical Technology , National and Kapodistrian University of Athens , Panepistimioupolis, Zografou 15771 , Greece.
  • Kiriakidi S; Department of Chemistry, Laboratory of Organic Chemistry , National and Kapodistrian University of Athens , Panepistimioupolis, Zografou 15771 , Greece.
  • Becker-Baldus J; Institute of Biophysical Chemistry , Goethe University Frankfurt , Max-von-Laue-Str. 9 , 60438 Frankfurt , Germany.
  • Stylos EK; Department of Chemistry, Section of Organic Chemistry and Biochemistry , University of Ioannina , Ioannina 45110 , Greece.
  • Chatziathanasiadou MV; Department of Biological Applications and Technology, Biotechnology Laboratory , University of Ioannina , Ioannina 45110 , Greece.
  • Chatzigiannis CM; Department of Chemistry, Section of Organic Chemistry and Biochemistry , University of Ioannina , Ioannina 45110 , Greece.
  • Damalas DE; Department of Chemistry, Section of Organic Chemistry and Biochemistry , University of Ioannina , Ioannina 45110 , Greece.
  • Aksoydan B; Department of Chemistry, Laboratory of Analytical Chemistry , National and Kapodistrian University of Athens , Panepistimioupolis, Zografou 15771 , Greece.
  • Javornik U; Department of Biophysics, Computational Biology and Molecular Simulations Laboratory , Bahcesehir University , Istanbul 34349 , Turkey.
  • Valsami G; National Institute of Chemistry, Slovenian NMR Centre , SI-1001 Ljubljana , Slovenia.
  • Glaubitz C; Department of Pharmacy, Laboratory of Pharmaceutical Technology , National and Kapodistrian University of Athens , Panepistimioupolis, Zografou 15771 , Greece.
  • Durdagi S; Institute of Biophysical Chemistry , Goethe University Frankfurt , Max-von-Laue-Str. 9 , 60438 Frankfurt , Germany.
  • Thomaidis NS; Department of Biophysics, Computational Biology and Molecular Simulations Laboratory , Bahcesehir University , Istanbul 34349 , Turkey.
  • Kolocouris A; Department of Chemistry, Laboratory of Analytical Chemistry , National and Kapodistrian University of Athens , Panepistimioupolis, Zografou 15771 , Greece.
  • Plavec J; Department of Pharmacy, Section of Pharmaceutical Chemistry , National and Kapodistrian University of Athens , Athens 15771 , Greece.
  • Tzakos AG; National Institute of Chemistry, Slovenian NMR Centre , SI-1001 Ljubljana , Slovenia.
  • Liapakis G; Department of Chemistry, Section of Organic Chemistry and Biochemistry , University of Ioannina , Ioannina 45110 , Greece.
  • Mavromoustakos T; Department of Pharmacology, School of Medicine , University of Crete , Heraklion, Crete 70013 , Greece.
Mol Pharm ; 16(3): 1255-1271, 2019 03 04.
Article em En | MEDLINE | ID: mdl-30681344
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tetrazóis / Benzimidazóis / Compostos de Bifenilo / Pró-Fármacos / Bloqueadores do Receptor Tipo 1 de Angiotensina II / Composição de Medicamentos / 2-Hidroxipropil-beta-Ciclodextrina Limite: Humans Idioma: En Revista: Mol Pharm Assunto da revista: BIOLOGIA MOLECULAR / FARMACIA / FARMACOLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Grécia País de publicação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tetrazóis / Benzimidazóis / Compostos de Bifenilo / Pró-Fármacos / Bloqueadores do Receptor Tipo 1 de Angiotensina II / Composição de Medicamentos / 2-Hidroxipropil-beta-Ciclodextrina Limite: Humans Idioma: En Revista: Mol Pharm Assunto da revista: BIOLOGIA MOLECULAR / FARMACIA / FARMACOLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Grécia País de publicação: Estados Unidos