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TALEN-Mediated Gene Editing of HBG in Human Hematopoietic Stem Cells Leads to Therapeutic Fetal Hemoglobin Induction.
Lux, Christopher T; Pattabhi, Sowmya; Berger, Mason; Nourigat, Cynthia; Flowers, David A; Negre, Olivier; Humbert, Olivier; Yang, Julia G; Lee, Calvin; Jacoby, Kyle; Bernstein, Irwin; Kiem, Hans-Peter; Scharenberg, Andrew; Rawlings, David J.
Afiliação
  • Lux CT; Center for Immunity and Immunotherapies and the Program for Cell and Gene Therapy, Seattle Children's Research Institute, Seattle, WA 98101, USA.
  • Pattabhi S; Department of Pediatrics, University of Washington, Seattle, WA 98195, USA.
  • Berger M; Center for Immunity and Immunotherapies and the Program for Cell and Gene Therapy, Seattle Children's Research Institute, Seattle, WA 98101, USA.
  • Nourigat C; Center for Immunity and Immunotherapies and the Program for Cell and Gene Therapy, Seattle Children's Research Institute, Seattle, WA 98101, USA.
  • Flowers DA; Stem Cell and Gene Therapy Program, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Negre O; Stem Cell and Gene Therapy Program, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Humbert O; bluebird bio, Inc., Cambridge MA 02142, USA.
  • Yang JG; Stem Cell and Gene Therapy Program, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Lee C; bluebird bio, Inc., Cambridge MA 02142, USA.
  • Jacoby K; bluebird bio, Inc., Cambridge MA 02142, USA.
  • Bernstein I; Center for Immunity and Immunotherapies and the Program for Cell and Gene Therapy, Seattle Children's Research Institute, Seattle, WA 98101, USA.
  • Kiem HP; Stem Cell and Gene Therapy Program, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Scharenberg A; Stem Cell and Gene Therapy Program, Fred Hutchinson Cancer Research Center, Seattle, WA 98109, USA.
  • Rawlings DJ; Department of Medicine, University of Washington, Seattle, WA 98195, USA.
Mol Ther Methods Clin Dev ; 12: 175-183, 2019 Mar 15.
Article em En | MEDLINE | ID: mdl-30705922

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: Mol Ther Methods Clin Dev Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Tipo de estudo: Prognostic_studies Idioma: En Revista: Mol Ther Methods Clin Dev Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos