Coefficient of variation of P-wave duration measured using an automated measurement system predicts recurrence of atrial fibrillation.
J Electrocardiol
; 53: 79-84, 2019.
Article
em En
| MEDLINE
| ID: mdl-30716526
ABSTRACT
BACKGROUND:
P-wave parameters representing atrial conduction heterogeneity are associated with recurrence of atrial fibrillation (AF) after catheter ablation. However, intra- and inter-observer variabilities are unavoidable during manual measurement of P-wave parameters.METHODS:
The study included 201 patients with paroxysmal AF who underwent catheter ablation. P-wave duration (PWD) was measured using a computerized automated measurement system with a surface 12-lead electrocardiogram. The coefficient of variation of PWD (CV-PWD) across the 12 electrocardiographic leads was determined as an index of atrial conduction heterogeneity.RESULTS:
AF did not recur in 157 (78%) patients during a 12-month follow-up period. CV-PWD assessed before catheter ablation was not different between the AF-recurrent and AF-free groups (0.069⯱â¯0.023 vs. 0.069⯱â¯0.023, Pâ¯=â¯0.090). However, CV-PWD measured after catheter ablation was significantly larger in the AF-recurrent group than in the AF-free group (0.090⯱â¯0.037 vs. 0.073⯱â¯0.024, Pâ¯<â¯0.001). In receiver operating curve analysis, CV-PWD assessed after catheter ablation achieved an area under the curve of 0.702; the sensitivity, specificity, and positive and negative predictive values were 68%, 69%, 38%, and 88%, respectively, for the cut-off value of 0.080. During the follow-up period, AF freedom rates of high CV-PWD patients (CV-PWDâ¯≥â¯0.080) and low CV-PWD patients (CV-PWDâ¯<â¯0.080) were 65% and 88%, respectively.CONCLUSIONS:
CV-PWD determined using an automated measurement system was associated with AF recurrence after catheter ablation in patients with paroxysmal AF.Palavras-chave
Texto completo:
1
Coleções:
01-internacional
Base de dados:
MEDLINE
Assunto principal:
Fibrilação Atrial
/
Ablação por Cateter
/
Eletrocardiografia
Tipo de estudo:
Observational_studies
/
Prognostic_studies
/
Risk_factors_studies
Limite:
Aged
/
Female
/
Humans
/
Male
/
Middle aged
País/Região como assunto:
Asia
Idioma:
En
Revista:
J Electrocardiol
Ano de publicação:
2019
Tipo de documento:
Article