Genetic and epigenetic alterations of the EGFR and mutually independent association with BRCA1, MGMT, and RASSF1A methylations in Vietnamese lung adenocarcinomas.

Nguyen, Quang Ngoc; Vuong, Linh Dieu; Truong, Van-Long; Ta, To Van; Nguyen, Nam Trung; Nguyen, Hung Phi; Chu, Ha Hoang

Nguyen, Quang Ngoc; Vuong, Linh Dieu; Truong, Van-Long; Ta, To Van; Nguyen, Nam Trung; Nguyen, Hung Phi; Chu, Ha Hoang.

Afiliação

Nguyen QN; Pathology and Molecular Biology Center, National Cancer Hospital K, 30 Cau Buou Street, Thanh Tri, Hanoi, Viet Nam; Biotechnology Department, Graduate University of Science and Technology, Academy of Science and Technology, 18 Hoang Quoc Viet Street, Cau Giay, Hanoi, Viet Nam. Electronic address: qu
Vuong LD; Pathology and Molecular Biology Center, National Cancer Hospital K, 30 Cau Buou Street, Thanh Tri, Hanoi, Viet Nam.
Truong VL; Department of Smart Food and Drug, College of BNIT, Inje University, Gimhae, 50834, South Korea.
Ta TV; Pathology and Molecular Biology Center, National Cancer Hospital K, 30 Cau Buou Street, Thanh Tri, Hanoi, Viet Nam.
Nguyen NT; National Key Laboratory of Gene Technology, Institute Vietnam, Academy of Science and Technology, 18 Hoang Quoc Viet Street, Cau Giay, Hanoi, Viet Nam; Biotechnology Department, Graduate University of Science and Technology, Academy of Science and Technology, 18 Hoang Quoc Viet Street, Cau Giay, Han
Nguyen HP; Pathology and Molecular Biology Center, National Cancer Hospital K, 30 Cau Buou Street, Thanh Tri, Hanoi, Viet Nam. Electronic address: phihung134@gmail.com.
Chu HH; National Key Laboratory of Gene Technology, Institute Vietnam, Academy of Science and Technology, 18 Hoang Quoc Viet Street, Cau Giay, Hanoi, Viet Nam; Biotechnology Department, Graduate University of Science and Technology, Academy of Science and Technology, 18 Hoang Quoc Viet Street, Cau Giay, Han

Pathol Res Pract ; 215(5): 885-892, 2019 May.

Article em En | MEDLINE | ID: mdl-30723053

Assuntos

Adenocarcinoma de Pulmão/genética; Metilação de DNA/genética; Epigênese Genética/genética; Neoplasias Pulmonares/genética; Adulto; Idoso; Idoso de 80 Anos ou mais; Povo Asiático/genética; Proteína BRCA1/genética; Biomarcadores Tumorais/genética; Metilases de Modificação do DNA/genética; Enzimas Reparadoras do DNA/genética; Receptores ErbB/genética; Feminino; Humanos; Masculino; Pessoa de Meia-Idade; Regiões Promotoras Genéticas/genética; Proteínas Supressoras de Tumor/genética

Palavras-chave

BRCA1; EGFR mutation; Lung adenocarcinomas; MGMT; Methylation; RASSF1A

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Metilação de DNA / Epigênese Genética / Adenocarcinoma de Pulmão / Neoplasias Pulmonares Tipo de estudo: Prognostic_studies / Risk_factors_studies Limite: Adult / Aged / Aged80 / Female / Humans / Male / Middle aged Idioma: En Revista: Pathol Res Pract Ano de publicação: 2019 Tipo de documento: Article País de publicação: Alemanha

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