Association of BER and NER pathway polymorphism haplotypes and micronucleus frequencies with global DNA methylation in benzene-exposed workers of China: Effects of DNA repair genes polymorphisms on genetic damage.

Zhang, Guang-Hui; Ren, Jing-Chao; Luo, Mengkai; Cui, Junpeng; Du, Yanqiu; Yang, Daokun; Cui, Shouming; Wang, Xiao; Wu, Weidong; Cao, Jia; Xia, Zhao-Lin

Zhang, Guang-Hui; Ren, Jing-Chao; Luo, Mengkai; Cui, Junpeng; Du, Yanqiu; Yang, Daokun; Cui, Shouming; Wang, Xiao; Wu, Weidong; Cao, Jia; Xia, Zhao-Lin.

Afiliação

Zhang GH; Henan Collaborative Innovation Center of Molecular Diagnosis and Laboratory Medicine, School of Public Health, Xinxiang Medical University, 601 Jinsui Road, Xinxiang, 453003, China. Electronic address: zhgh221@163.com.
Ren JC; Henan Collaborative Innovation Center of Molecular Diagnosis and Laboratory Medicine, School of Public Health, Xinxiang Medical University, 601 Jinsui Road, Xinxiang, 453003, China.
Luo M; Henan Collaborative Innovation Center of Molecular Diagnosis and Laboratory Medicine, School of Public Health, Xinxiang Medical University, 601 Jinsui Road, Xinxiang, 453003, China.
Cui J; Henan Collaborative Innovation Center of Molecular Diagnosis and Laboratory Medicine, School of Public Health, Xinxiang Medical University, 601 Jinsui Road, Xinxiang, 453003, China.
Du Y; Department of Occupational Health and Toxicology, School of Public Health, Fudan University, 138 Yixueyuan Road, Shanghai, 200032, China.
Yang D; Henan Collaborative Innovation Center of Molecular Diagnosis and Laboratory Medicine, School of Public Health, Xinxiang Medical University, 601 Jinsui Road, Xinxiang, 453003, China.
Cui S; Xinxiang Academy of Occupational Health and Occupational Medicine, 32 Rongjiao Road, Xinxiang, 453003, China.
Wang X; Henan Collaborative Innovation Center of Molecular Diagnosis and Laboratory Medicine, School of Public Health, Xinxiang Medical University, 601 Jinsui Road, Xinxiang, 453003, China.
Wu W; Henan Collaborative Innovation Center of Molecular Diagnosis and Laboratory Medicine, School of Public Health, Xinxiang Medical University, 601 Jinsui Road, Xinxiang, 453003, China.
Cao J; Henan Collaborative Innovation Center of Molecular Diagnosis and Laboratory Medicine, School of Public Health, Xinxiang Medical University, 601 Jinsui Road, Xinxiang, 453003, China. Electronic address: caojia1962@126.com.
Xia ZL; Department of Occupational Health and Toxicology, School of Public Health, Fudan University, 138 Yixueyuan Road, Shanghai, 200032, China. Electronic address: zlxia@shmu.edu.cn.

Mutat Res Genet Toxicol Environ Mutagen ; 839: 13-20, 2019 Mar.

Article em En | MEDLINE | ID: mdl-30744808

Assuntos

Benzeno/efeitos adversos; Biomarcadores/análise; Dano ao DNA; Metilação de DNA; Reparo do DNA; Exposição Ocupacional/efeitos adversos; Polimorfismo de Nucleotídeo Único; Proteína 1 Complementadora Cruzada de Reparo de Raio-X/metabolismo; Adulto; Estudos de Casos e Controles; DNA Liase (Sítios Apurínicos ou Apirimidínicos)/genética; Proteínas de Ligação a DNA/genética; Endonucleases/genética; Genoma Humano; Haplótipos; Humanos; Masculino; Testes para Micronúcleos; Proteínas Nucleares/genética; Prognóstico; Fatores de Transcrição/genética; Proteína 1 Complementadora Cruzada de Reparo de Raio-X/genética; Proteína de Xeroderma Pigmentoso Grupo A/genética; Proteína Grupo D do Xeroderma Pigmentoso/genética

Palavras-chave

Base excision repair; Benzene; Global DNA methylation; Micronucleus; Nucleotide excision repair; Single nucleotide polymorphisms

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Benzeno / Dano ao DNA / Biomarcadores / Exposição Ocupacional / Metilação de DNA / Polimorfismo de Nucleotídeo Único / Reparo do DNA / Proteína 1 Complementadora Cruzada de Reparo de Raio-X Tipo de estudo: Observational_studies / Prognostic_studies / Risk_factors_studies Limite: Adult / Humans / Male Idioma: En Revista: Mutat Res Genet Toxicol Environ Mutagen Ano de publicação: 2019 Tipo de documento: Article País de publicação: Holanda

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