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In Vitro Cytotoxicity of Zinc Fructoborate, a Novel Zinc-Boron Active Natural Complex.
Oancea, C N; Cîmpean, A; Ion, R; Neamtu, J; Bita, A; Scorei, I R; Neamtu, A S; Rogoveanu, O C; Zaharie, S I; Birkenmeier, G.
Afiliação
  • Oancea CN; PhD Student, Doctoral School, University of Medicine and Pharmacy of Craiova, Romania.
  • Cîmpean A; Department of Biochemistry and Molecular Biology, Faculty of Biology, University of Bucharest, Romania.
  • Ion R; Department of Biochemistry and Molecular Biology, Faculty of Biology, University of Bucharest, Romania.
  • Neamtu J; Department of Physics, Faculty of Pharmacy, University of Medicine and Pharmacy of Craiova, Romania.
  • Bita A; Department of Pharmacognosy & Phytotherapy, Faculty of Pharmacy,University of Medicine and Pharmacy of Craiova, Romania.
  • Scorei IR; 5Research Base of Boron Natural Compounds-BioBoron Institute, S.C. Natural Research S.R.L. Craiova, Romania.
  • Neamtu AS; PhD Student, Doctoral School, University of Medicine and Pharmacy of Craiova, Romania.
  • Rogoveanu OC; Department of Medical Rehabilitation, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, Romania.
  • Zaharie SI; Department of Nephrology, Faculty of Medicine, University of Medicine and Pharmacy of Craiova, Romania.
  • Birkenmeier G; Institute of Biochemistry, Faculty of Medicine, University of Leipzig, Germany.
Curr Health Sci J ; 44(2): 113-117, 2018.
Article em En | MEDLINE | ID: mdl-30746157
ABSTRACT
In recent years, the role of zinc in biological systems has been a subject of intense research. Zinc is required for multiple metabolic processes as a structural, regulatory, or catalytic ion. The objective of this study, was to assess the toxicity profile of a newly synthesized zinc-boron molecule on cultured cells. Zinc fructoborate, at different levels of concentration, was tested for its impact on the Vero kidney cell line (ATCC® CCL-81™) using the MTT assay. The compound exhibited a low cytotoxic effect on the cell line. Thus, our study demonstrates that the zinc fructoborate could become a promising dietary supplement molecule.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Curr Health Sci J Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Romênia

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: Curr Health Sci J Ano de publicação: 2018 Tipo de documento: Article País de afiliação: Romênia