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What doesn't kill you makes you stranger: Dipeptidyl peptidase-4 (CD26) proteolysis differentially modulates the activity of many peptide hormones and cytokines generating novel cryptic bioactive ligands.
Elmansi, Ahmed M; Awad, Mohamed E; Eisa, Nada H; Kondrikov, Dmitry; Hussein, Khaled A; Aguilar-Pérez, Alexandra; Herberg, Samuel; Periyasamy-Thandavan, Sudharsan; Fulzele, Sadanand; Hamrick, Mark W; McGee-Lawrence, Meghan E; Isales, Carlos M; Volkman, Brian F; Hill, William D.
Afiliação
  • Elmansi AM; Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, SC 29403, United States; Ralph H. Johnson Veterans Affairs Medical Center, Charleston, SC 29403, United States.
  • Awad ME; Department of Oral Biology, School of Dentistry, Augusta University, Augusta, GA 30912, United States.
  • Eisa NH; Georgia Cancer Center, Augusta University, Augusta, GA 30912, United States; Department of Biochemistry, Faculty of Pharmacy, Mansoura University, Mansoura, 35516, Egypt.
  • Kondrikov D; Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, SC 29403, United States; Ralph H. Johnson Veterans Affairs Medical Center, Charleston, SC 29403, United States.
  • Hussein KA; Department of Surgery and Medicine, National Research Centre, Cairo, Egypt.
  • Aguilar-Pérez A; Department of Anatomy and Cell Biology, Indiana University School of Medicine in Indianapolis, IN, United States; Department of Cellular and Molecular Biology, School of Medicine, Universidad Central del Caribe, Bayamon, 00956, Puerto Rico; Cellular Biology and Anatomy, Medical College of Georgia, A
  • Herberg S; Departments of Ophthalmology & Cell and Dev. Bio., SUNY Upstate Medical University, Syracuse, NY 13210, United States.
  • Periyasamy-Thandavan S; Georgia Cancer Center, Augusta University, Augusta, GA 30912, United States.
  • Fulzele S; Department of Orthopaedic Surgery, Medical College of Georgia, Augusta University, Augusta, GA 30912, United States; Center for Healthy Aging, Medical College of Georgia, Augusta University, Augusta, GA, 30912, United States.
  • Hamrick MW; Cellular Biology and Anatomy, Medical College of Georgia, Augusta University, Augusta, GA 30912, United States; Department of Orthopaedic Surgery, Medical College of Georgia, Augusta University, Augusta, GA 30912, United States; Center for Healthy Aging, Medical College of Georgia, Augusta Universit
  • McGee-Lawrence ME; Cellular Biology and Anatomy, Medical College of Georgia, Augusta University, Augusta, GA 30912, United States; Department of Orthopaedic Surgery, Medical College of Georgia, Augusta University, Augusta, GA 30912, United States; Center for Healthy Aging, Medical College of Georgia, Augusta Universit
  • Isales CM; Department of Orthopaedic Surgery, Medical College of Georgia, Augusta University, Augusta, GA 30912, United States; Center for Healthy Aging, Medical College of Georgia, Augusta University, Augusta, GA, 30912, United States; Division of Endocrinology, Diabetes and Metabolism, Medical College of Geo
  • Volkman BF; Biochemistry Department, Medical College of Wisconsin, Milwaukee, WI 53226, United States.
  • Hill WD; Department of Pathology and Laboratory Medicine, Medical University of South Carolina, Charleston, SC 29403, United States; Ralph H. Johnson Veterans Affairs Medical Center, Charleston, SC 29403, United States; Cellular Biology and Anatomy, Medical College of Georgia, Augusta University, Augusta, GA
Pharmacol Ther ; 198: 90-108, 2019 06.
Article em En | MEDLINE | ID: mdl-30759373

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Citocinas / Dipeptidil Peptidase 4 / Hormônios Peptídicos Limite: Animals / Humans Idioma: En Revista: Pharmacol Ther Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Citocinas / Dipeptidil Peptidase 4 / Hormônios Peptídicos Limite: Animals / Humans Idioma: En Revista: Pharmacol Ther Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos