Tumor Microenvironment-Activatable Prodrug Vesicles for Nanoenabled Cancer Chemoimmunotherapy Combining Immunogenic Cell Death Induction and CD47 Blockade.

Zhou, Fangyuan; Feng, Bing; Yu, Haijun; Wang, Dangge; Wang, Tingting; Ma, Yuting; Wang, Siling; Li, Yaping

Zhou, Fangyuan; Feng, Bing; Yu, Haijun; Wang, Dangge; Wang, Tingting; Ma, Yuting; Wang, Siling; Li, Yaping.

Afiliação

Zhou F; State Key Laboratory of Drug Research and Center of Pharmaceutics, Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CAS), Shanghai, 201203, China.
Feng B; School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, 110016, China.
Yu H; State Key Laboratory of Drug Research and Center of Pharmaceutics, Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CAS), Shanghai, 201203, China.
Wang D; Chinese Academy of Sciences (UCAS), Beijing, 100049, China.
Wang T; State Key Laboratory of Drug Research and Center of Pharmaceutics, Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CAS), Shanghai, 201203, China.
Ma Y; State Key Laboratory of Drug Research and Center of Pharmaceutics, Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CAS), Shanghai, 201203, China.
Wang S; Chinese Academy of Sciences (UCAS), Beijing, 100049, China.
Li Y; State Key Laboratory of Drug Research and Center of Pharmaceutics, Shanghai Institute of Materia Medica, Chinese Academy of Sciences (CAS), Shanghai, 201203, China.

Adv Mater ; 31(14): e1805888, 2019 Apr.

Article em En | MEDLINE | ID: mdl-30762908

Assuntos

Antígeno CD47/antagonistas & inibidores; Morte Celular/efeitos dos fármacos; Morte Celular/imunologia; Imunoterapia/métodos; Nanoestruturas/química; Pró-Fármacos/metabolismo; Microambiente Tumoral/efeitos dos fármacos; Animais; Humanos; Pró-Fármacos/química; Microambiente Tumoral/imunologia

Palavras-chave

CD47 blockade; cancer immunotherapy; immunogenic cell death; prodrug vesicles; tumor microenvironment

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pró-Fármacos / Morte Celular / Nanoestruturas / Antígeno CD47 / Microambiente Tumoral / Imunoterapia Limite: Animals / Humans Idioma: En Revista: Adv Mater Assunto da revista: BIOFISICA / QUIMICA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China País de publicação: Alemanha

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