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Investigation on the effect of alkyl chain linked mono-thioureas as Jack bean urease inhibitors, SAR, pharmacokinetics ADMET parameters and molecular docking studies.
Larik, Fayaz Ali; Faisal, Muhammad; Saeed, Aamer; Channar, Pervaiz Ali; Korabecny, Jan; Jabeen, Farukh; Mahar, Ihsan Ali; Kazi, Mehar Ali; Abbas, Qamar; Murtaza, Ghulam; Khan, Gul Shahzada; Hassan, Mubashir; Seo, Sung-Yum.
Afiliação
  • Larik FA; Department of Chemistry, Quaid-I-Azam University, Islamabad 45320, Pakistan. Electronic address: fayazali@chem.qau.edu.pk.
  • Faisal M; Department of Chemistry, Quaid-I-Azam University, Islamabad 45320, Pakistan. Electronic address: mfaisal4646@gmail.com.
  • Saeed A; Department of Chemistry, Quaid-I-Azam University, Islamabad 45320, Pakistan. Electronic address: aamersaeed@yahoo.com.
  • Channar PA; Department of Chemistry, Quaid-I-Azam University, Islamabad 45320, Pakistan.
  • Korabecny J; Biomedical Research Centre, University Hospital Hradec Kralove, Sokolska 581, 500 05 Hradec Kralove, Czech Republic.
  • Jabeen F; Cardiovascular and Metabolic Research Unit, Laurentian University, 935 Ramsey Lake Road, Sudbury, ON P3E 2C6, Canada.
  • Mahar IA; Department of Chemistry, Quaid-I-Azam University, Islamabad 45320, Pakistan.
  • Kazi MA; Institute of biochemistry, University of Sindh, Jamshoro 76080, Pakistan.
  • Abbas Q; Department of Physiology, University of Sindh, Jamshoro 76080, Pakistan.
  • Murtaza G; Department of Chemistry, Quaid-I-Azam University, Islamabad 45320, Pakistan.
  • Khan GS; Department of Chemistry, Abdul Wali Khan University, Mardan, Khybder Pakhtunkhwa, Pakistan.
  • Hassan M; Department of Biological Sciences, College of Natural Sciences, Kongju National University, 56 Gongjudehak-Ro, Gongju, Chungnam 314-701, Republic of Korea.
  • Seo SY; Department of Biological Sciences, College of Natural Sciences, Kongju National University, 56 Gongjudehak-Ro, Gongju, Chungnam 314-701, Republic of Korea.
Bioorg Chem ; 86: 473-481, 2019 05.
Article em En | MEDLINE | ID: mdl-30772648
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tioureia / Urease / Canavalia / Inibidores Enzimáticos / Simulação de Acoplamento Molecular Tipo de estudo: Prognostic_studies Idioma: En Revista: Bioorg Chem Ano de publicação: 2019 Tipo de documento: Article País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Tioureia / Urease / Canavalia / Inibidores Enzimáticos / Simulação de Acoplamento Molecular Tipo de estudo: Prognostic_studies Idioma: En Revista: Bioorg Chem Ano de publicação: 2019 Tipo de documento: Article País de publicação: Estados Unidos