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Development of Highly Potent, Selective, and Cellular Active Triazolo[1,5- a]pyrimidine-Based Inhibitors Targeting the DCN1-UBC12 Protein-Protein Interaction.
Wang, Shuai; Zhao, Lijie; Shi, Xiao-Jing; Ding, Lina; Yang, Linlin; Wang, Zhi-Zheng; Shen, Dandan; Tang, Kai; Li, Xiao-Jing; Mamun, Maa; Li, Huiju; Yu, Bin; Zheng, Yi-Chao; Wang, Shaomeng; Liu, Hong-Min.
Afiliação
  • Wang S; School of Pharmaceutical Sciences and Institute of Drug Discovery & Development , Zhengzhou University , Zhengzhou 450001 , China.
  • Zhao L; Co-Innovation Center of Henan Province for New Drug R & D and Preclinical Safety , Zhengzhou 450001 , China.
  • Shi XJ; Key Laboratory of Advanced Technology of Drug Preparation Technologies, Zhengzhou University, Ministry of Education of China, Zhengzhou 450001 , China.
  • Ding L; School of Pharmaceutical Sciences and Institute of Drug Discovery & Development , Zhengzhou University , Zhengzhou 450001 , China.
  • Yang L; Co-Innovation Center of Henan Province for New Drug R & D and Preclinical Safety , Zhengzhou 450001 , China.
  • Wang ZZ; Key Laboratory of Advanced Technology of Drug Preparation Technologies, Zhengzhou University, Ministry of Education of China, Zhengzhou 450001 , China.
  • Shen D; School of Pharmaceutical Sciences and Institute of Drug Discovery & Development , Zhengzhou University , Zhengzhou 450001 , China.
  • Tang K; Co-Innovation Center of Henan Province for New Drug R & D and Preclinical Safety , Zhengzhou 450001 , China.
  • Li XJ; Key Laboratory of Advanced Technology of Drug Preparation Technologies, Zhengzhou University, Ministry of Education of China, Zhengzhou 450001 , China.
  • Mamun M; School of Pharmaceutical Sciences and Institute of Drug Discovery & Development , Zhengzhou University , Zhengzhou 450001 , China.
  • Li H; Co-Innovation Center of Henan Province for New Drug R & D and Preclinical Safety , Zhengzhou 450001 , China.
  • Yu B; Key Laboratory of Advanced Technology of Drug Preparation Technologies, Zhengzhou University, Ministry of Education of China, Zhengzhou 450001 , China.
  • Zheng YC; Department of Pharmacology, School of Basic Medical Sciences , Zhengzhou University , Zhengzhou 450001 , China.
  • Wang S; School of Pharmaceutical Sciences and Institute of Drug Discovery & Development , Zhengzhou University , Zhengzhou 450001 , China.
  • Liu HM; Co-Innovation Center of Henan Province for New Drug R & D and Preclinical Safety , Zhengzhou 450001 , China.
J Med Chem ; 62(5): 2772-2797, 2019 03 14.
Article em En | MEDLINE | ID: mdl-30803229
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirimidinas / Triazóis / Enzimas de Conjugação de Ubiquitina / Peptídeos e Proteínas de Sinalização Intracelular Limite: Humans Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China País de publicação: Estados Unidos
Texto completo
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Pirimidinas / Triazóis / Enzimas de Conjugação de Ubiquitina / Peptídeos e Proteínas de Sinalização Intracelular Limite: Humans Idioma: En Revista: J Med Chem Assunto da revista: QUIMICA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China País de publicação: Estados Unidos