Reversal of carbapenem-resistance in <i>Shewanella algae</i> by CRISPR/Cas9 genome editing.

Wu, Zong-Yen; Huang, Yao-Ting; Chao, Wen-Cheng; Ho, Shu-Peng; Cheng, Jan-Fang; Liu, Po-Yu

Reversal of carbapenem-resistance in Shewanella algae by CRISPR/Cas9 genome editing.

Wu, Zong-Yen; Huang, Yao-Ting; Chao, Wen-Cheng; Ho, Shu-Peng; Cheng, Jan-Fang; Liu, Po-Yu.

Afiliação

Wu ZY; US Department of Energy Joint Genome Institute, Walnut Creek, CA, USA.
Huang YT; Department of Veterinary Medicine, National Chung Hsing University, Taichung, Taiwan.
Chao WC; Department of Computer Science and Information Engineering, National Chung Cheng University, Chia-Yi, Taiwan.
Ho SP; Department of Medical Research, Taichung Veterans General Hospital, Taichung, Taiwan.
Cheng JF; Department of Veterinary Medicine, National Chung Hsing University, Taichung, Taiwan.
Liu PY; US Department of Energy Joint Genome Institute, Walnut Creek, CA, USA.

J Adv Res ; 18: 61-69, 2019 Jul.

Article em En | MEDLINE | ID: mdl-30809393

Palavras-chave

Beta-lactamase OXA-55; COGs, Clusters of Orthologous Groups of proteins; CRISPR, clustered regularly interspaced short palindromic repeat; CRISPR-Cas9; Carbapenem; Cas9, CRISPR-associated protein 9; DAP, diaminopimelic acid; NCBI, National Center for Biotechnology Information; PGAAP, Prokaryotic Genomes Automatic Annotation Pipeline; Resistance; SMRT, single-molecule real-time; Shewanella algae

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: J Adv Res Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Egito

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