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Berberine prevents human nucleus pulposus cells from IL­1ß­induced extracellular matrix degradation and apoptosis by inhibiting the NF­κB pathway.
Lu, Lin; Hu, Jialang; Wu, Qipeng; An, Ying; Cui, Wei; Wang, Junwen; Ye, Zhewei.
Afiliação
  • Lu L; Department of Orthopaedics, Wuhan Fourth Hospital; Puai Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430033, P.R. China.
  • Hu J; Department of Orthopaedics, Wuhan Fourth Hospital; Puai Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430033, P.R. China.
  • Wu Q; Department of Orthopaedics, Wuhan Fourth Hospital; Puai Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430033, P.R. China.
  • An Y; Department of Orthopaedics, Wuhan Fourth Hospital; Puai Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430033, P.R. China.
  • Cui W; Department of Orthopaedics, Wuhan Fourth Hospital; Puai Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430033, P.R. China.
  • Wang J; Department of Orthopaedics, Wuhan Fourth Hospital; Puai Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430033, P.R. China.
  • Ye Z; Department of Orthopaedics, Union Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, Hubei 430022, P.R. China.
Int J Mol Med ; 43(4): 1679-1686, 2019 Apr.
Article em En | MEDLINE | ID: mdl-30816449
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Berberina / Transdução de Sinais / NF-kappa B / Apoptose / Matriz Extracelular / Interleucina-1beta / Núcleo Pulposo Tipo de estudo: Prognostic_studies Limite: Adolescent / Adult / Humans Idioma: En Revista: Int J Mol Med Assunto da revista: BIOLOGIA MOLECULAR / GENETICA MEDICA Ano de publicação: 2019 Tipo de documento: Article País de publicação: Grécia
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Berberina / Transdução de Sinais / NF-kappa B / Apoptose / Matriz Extracelular / Interleucina-1beta / Núcleo Pulposo Tipo de estudo: Prognostic_studies Limite: Adolescent / Adult / Humans Idioma: En Revista: Int J Mol Med Assunto da revista: BIOLOGIA MOLECULAR / GENETICA MEDICA Ano de publicação: 2019 Tipo de documento: Article País de publicação: Grécia