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Identification of the Raf kinase inhibitor TAK-632 and its analogues as potent inhibitors of necroptosis by targeting RIPK1 and RIPK3.
Chen, Xiaofei; Zhuang, Chunlin; Ren, Yibin; Zhang, Hao; Qin, Xia; Hu, Longmiao; Fu, Jing; Miao, Zhenyuan; Chai, Yifeng; Liu, Zheng-Gang; Zhang, Haibing; Cai, Zhenyu; Wang, Hong-Yang.
Afiliação
  • Chen X; National Center for Liver Cancer, Second Military Medical University, Shanghai, China.
  • Zhuang C; The International Cooperation Laboratory on Signal Transduction, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China.
  • Ren Y; School of Pharmacy, Second Military Medical University, Shanghai, China.
  • Zhang H; School of Pharmacy, Second Military Medical University, Shanghai, China.
  • Qin X; School of Pharmacy, Ningxia Medical University, Yinchuan, China.
  • Hu L; National Center for Liver Cancer, Second Military Medical University, Shanghai, China.
  • Fu J; School of Pharmacy, Ningxia Medical University, Yinchuan, China.
  • Miao Z; National Center for Liver Cancer, Second Military Medical University, Shanghai, China.
  • Chai Y; The International Cooperation Laboratory on Signal Transduction, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China.
  • Liu ZG; National Center for Liver Cancer, Second Military Medical University, Shanghai, China.
  • Zhang H; The International Cooperation Laboratory on Signal Transduction, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China.
  • Cai Z; National Center for Liver Cancer, Second Military Medical University, Shanghai, China.
  • Wang HY; The International Cooperation Laboratory on Signal Transduction, Eastern Hepatobiliary Surgery Hospital, Second Military Medical University, Shanghai, China.
Br J Pharmacol ; 176(12): 2095-2108, 2019 06.
Article em En | MEDLINE | ID: mdl-30825190
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inibidores de Proteínas Quinases / Benzotiazóis / Proteína Serina-Treonina Quinases de Interação com Receptores / Necroptose / Nitrilas Tipo de estudo: Diagnostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Br J Pharmacol Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Inibidores de Proteínas Quinases / Benzotiazóis / Proteína Serina-Treonina Quinases de Interação com Receptores / Necroptose / Nitrilas Tipo de estudo: Diagnostic_studies Limite: Animals / Female / Humans Idioma: En Revista: Br J Pharmacol Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China País de publicação: Reino Unido