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Design, Synthesis and Biological Evaluation of Isoxazole-Based CK1 Inhibitors Modified with Chiral Pyrrolidine Scaffolds.
Luxenburger, Andreas; Schmidt, Dorian; Ianes, Chiara; Pichlo, Christian; Krüger, Marc; von Drathen, Thorsten; Brunstein, Elena; Gainsford, Graeme J; Baumann, Ulrich; Knippschild, Uwe; Peifer, Christian.
Afiliação
  • Luxenburger A; Ferrier Research Institute, Victoria University of Wellington, 69 Gracefield Rd, Lower Hutt 5040, New Zealand. Andreas.Luxenburger@vuw.ac.nz.
  • Schmidt D; Institute of Pharmacy, Christian-Albrechts-University of Kiel, Gutenbergstraße 76, D-24116 Kiel, Germany. dschmidt@pharmazie.uni-kiel.de.
  • Ianes C; Department of General and Visceral Surgery, Ulm University Hospital, Albert-Einstein-Allee 23, D-89081 Ulm, Germany. chiara.ianes@uni-ulm.de.
  • Pichlo C; Institute of Biochemistry, University of Cologne, Zuelpicher Str. 47, D-50674 Cologne, Germany. pichloc@uni-koeln.de.
  • Krüger M; Department of General and Visceral Surgery, Ulm University Hospital, Albert-Einstein-Allee 23, D-89081 Ulm, Germany. marcm3012@googlemail.com.
  • von Drathen T; Institute of Pharmacy, Christian-Albrechts-University of Kiel, Gutenbergstraße 76, D-24116 Kiel, Germany. T.vonDrathen@gmx.de.
  • Brunstein E; Institute of Biochemistry, University of Cologne, Zuelpicher Str. 47, D-50674 Cologne, Germany. Elena.Brunstein@uni-koeln.de.
  • Gainsford GJ; Ferrier Research Institute, Victoria University of Wellington, 69 Gracefield Rd, Lower Hutt 5040, New Zealand. gjgainsford@gmail.com.
  • Baumann U; Institute of Biochemistry, University of Cologne, Zuelpicher Str. 47, D-50674 Cologne, Germany. ubaumann@uni-koeln.de.
  • Knippschild U; Department of General and Visceral Surgery, Ulm University Hospital, Albert-Einstein-Allee 23, D-89081 Ulm, Germany. uwe.knippschild@uniklinik-ulm.de.
  • Peifer C; Institute of Pharmacy, Christian-Albrechts-University of Kiel, Gutenbergstraße 76, D-24116 Kiel, Germany. cpeifer@pharmazie.uni-kiel.de.
Molecules ; 24(5)2019 Mar 01.
Article em En | MEDLINE | ID: mdl-30832206
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Desenho de Fármacos / Caseína Quinase Idelta / Inibidores Enzimáticos / Isoxazóis Limite: Humans Idioma: En Revista: Molecules Assunto da revista: BIOLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Nova Zelândia País de publicação: Suíça
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Desenho de Fármacos / Caseína Quinase Idelta / Inibidores Enzimáticos / Isoxazóis Limite: Humans Idioma: En Revista: Molecules Assunto da revista: BIOLOGIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Nova Zelândia País de publicação: Suíça