G-Quadruplex Structure Improves the Immunostimulatory Effects of CpG Oligonucleotides.

Hoshi, Kazuaki; Yamazaki, Tomohiko; Sugiyama, Yuuki; Tsukakoshi, Kaori; Tsugawa, Wakako; Sode, Koji; Ikebukuro, Kazunori

Hoshi, Kazuaki; Yamazaki, Tomohiko; Sugiyama, Yuuki; Tsukakoshi, Kaori; Tsugawa, Wakako; Sode, Koji; Ikebukuro, Kazunori.

Afiliação

Hoshi K; 1Department of Biotechnology and Life Science, Graduate School of Engineering, Tokyo University of Agriculture and Technology, Tokyo, Japan.
Yamazaki T; 2Research Center for Functional Materials, National Institute for Materials Science (NIMS), Tsukuba, Japan.
Sugiyama Y; 1Department of Biotechnology and Life Science, Graduate School of Engineering, Tokyo University of Agriculture and Technology, Tokyo, Japan.
Tsukakoshi K; 1Department of Biotechnology and Life Science, Graduate School of Engineering, Tokyo University of Agriculture and Technology, Tokyo, Japan.
Tsugawa W; 1Department of Biotechnology and Life Science, Graduate School of Engineering, Tokyo University of Agriculture and Technology, Tokyo, Japan.
Sode K; 3Joint Department of Biomedical Engineering, The University of North Carolina at Chapel Hill and North Carolina State University, Chapel Hill, North Carolina.
Ikebukuro K; 1Department of Biotechnology and Life Science, Graduate School of Engineering, Tokyo University of Agriculture and Technology, Tokyo, Japan.

Nucleic Acid Ther ; 29(4): 224-229, 2019 08.

Article em En | MEDLINE | ID: mdl-30835633

Assuntos

Quadruplex G; Leucócitos Mononucleares/imunologia; Oligonucleotídeos Antissenso/genética; Adjuvantes Imunológicos/genética; Adjuvantes Imunológicos/farmacologia; Animais; Linhagem Celular; Ilhas de CpG/efeitos dos fármacos; Humanos; Fatores Imunológicos/genética; Leucócitos Mononucleares/efeitos dos fármacos; Conformação de Ácido Nucleico/efeitos dos fármacos; Oligonucleotídeos Antissenso/química; Fosfatos/química; Fosfatos/metabolismo

Palavras-chave

CpG ODN; G-quadruplex; IL-6; peripheral blood mononuclear cells; toll-like receptor 9

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Leucócitos Mononucleares / Oligonucleotídeos Antissenso / Quadruplex G Limite: Animals / Humans Idioma: En Revista: Nucleic Acid Ther Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Japão País de publicação: Estados Unidos

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google