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GNAI1 and GNAI3 Reduce Colitis-Associated Tumorigenesis in Mice by Blocking IL6 Signaling and Down-regulating Expression of GNAI2.
Li, Zhi-Wei; Sun, Beicheng; Gong, Ting; Guo, Sheng; Zhang, Jianhua; Wang, Junlong; Sugawara, Atsushi; Jiang, Meisheng; Yan, Junjun; Gurary, Alexandra; Zheng, Xin; Gao, Bifeng; Xiao, Shu-Yuan; Chen, Wenlian; Ma, Chi; Farrar, Christine; Zhu, Chenjun; Chan, Owen T M; Xin, Can; Winnicki, Andrew; Winnicki, John; Tang, Mingxin; Park, Ryan; Winnicki, Mary; Diener, Katrina; Wang, Zhanwei; Liu, Qicai; Chu, Catherine H; Arter, Zhaohui L; Yue, Peibin; Alpert, Lindsay; Hui, George S; Fei, Peiwen; Turkson, James; Yang, Wentian; Wu, Guangyu; Tao, Ailin; Ramos, Joe W; Moisyadi, Stefan; Holcombe, Randall F; Jia, Wei; Birnbaumer, Lutz; Zhou, Xiqiao; Chu, Wen-Ming.
Afiliação
  • Li ZW; Cancer Biology Program, University of Hawaii Cancer Center, Honolulu, Hawaii.
  • Sun B; Department of Hepatobiliary Surgery, The Affiliated Drum Tower Hospital of Nanjing University Medical School, Nanjing, Jiangsu, China.
  • Gong T; Cancer Biology Program, University of Hawaii Cancer Center, Honolulu, Hawaii.
  • Guo S; Cancer Biology Program, University of Hawaii Cancer Center, Honolulu, Hawaii; Department of Endocrine, Genetics and Metabolism, Shanghai Children's Hospital, Shanghai Jiao Tong University, Shanghai, China.
  • Zhang J; Cancer Biology Program, University of Hawaii Cancer Center, Honolulu, Hawaii; Department of Pediatrics, Xinhua Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China.
  • Wang J; Cancer Biology Program, University of Hawaii Cancer Center, Honolulu, Hawaii.
  • Sugawara A; Institute for Biogenesis Research, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii.
  • Jiang M; Department of Molecular and Medical Pharmacology, University of California, Los Angeles, California.
  • Yan J; Department of Gastroenterology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China.
  • Gurary A; Department of Tropical Medicine, Medical Microbiology, and Pharmacology, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii.
  • Zheng X; Cancer Biology Program, University of Hawaii Cancer Center, Honolulu, Hawaii.
  • Gao B; Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado.
  • Xiao SY; Department of Pathology, Zhongnan Hospital of Wuhan University, Wuhan, Hubei, China; Department of Pathology, University of Chicago, Chicago, Illinois.
  • Chen W; Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii.
  • Ma C; Cancer Biology Program, University of Hawaii Cancer Center, Honolulu, Hawaii.
  • Farrar C; The Microscopy, Imaging, and Flow Cytometry Shared Resource, University of Hawaii Cancer Center, Honolulu, Hawaii.
  • Zhu C; Cancer Biology Program, University of Hawaii Cancer Center, Honolulu, Hawaii.
  • Chan OTM; Pathology Core, University of Hawaii Cancer Center, Honolulu, Hawaii.
  • Xin C; Cancer Biology Program, University of Hawaii Cancer Center, Honolulu, Hawaii.
  • Winnicki A; Cancer Biology Program, University of Hawaii Cancer Center, Honolulu, Hawaii.
  • Winnicki J; Cancer Biology Program, University of Hawaii Cancer Center, Honolulu, Hawaii.
  • Tang M; Center for Cardiovascular Research, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii.
  • Park R; Cancer Biology Program, University of Hawaii Cancer Center, Honolulu, Hawaii.
  • Winnicki M; Cancer Biology Program, University of Hawaii Cancer Center, Honolulu, Hawaii.
  • Diener K; Department of Medicine, University of Colorado Anschutz Medical Campus, Aurora, Colorado.
  • Wang Z; Cancer Biology Program, University of Hawaii Cancer Center, Honolulu, Hawaii.
  • Liu Q; Cancer Biology Program, University of Hawaii Cancer Center, Honolulu, Hawaii; Department of Cardiology and Heart Center, Zhujiang Hospital, Southern Medical University, Guangzhou, Guangdong, China.
  • Chu CH; Cancer Biology Program, University of Hawaii Cancer Center, Honolulu, Hawaii.
  • Arter ZL; Cancer Biology Program, University of Hawaii Cancer Center, Honolulu, Hawaii.
  • Yue P; Cancer Biology Program, University of Hawaii Cancer Center, Honolulu, Hawaii.
  • Alpert L; Department of Pathology, University of Chicago, Chicago, Illinois.
  • Hui GS; Department of Tropical Medicine, Medical Microbiology, and Pharmacology, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii.
  • Fei P; Cancer Biology Program, University of Hawaii Cancer Center, Honolulu, Hawaii.
  • Turkson J; Cancer Biology Program, University of Hawaii Cancer Center, Honolulu, Hawaii.
  • Yang W; Department of Orthopedics, Rhode Island Hospital, Brown University Alpert Medical School, Providence, Rhode Island.
  • Wu G; Department of Pharmacology and Toxicology, Augusta University, Augusta, Georgia.
  • Tao A; The Second Affiliated Hospital, The State Key Laboratory of Respiratory Disease, Guangdong Provincial Key Laboratory of Allergy and Clinical Immunology, Guangzhou Medical University, Guangzhou, Guangdong, China.
  • Ramos JW; Cancer Biology Program, University of Hawaii Cancer Center, Honolulu, Hawaii.
  • Moisyadi S; Institute for Biogenesis Research, John A. Burns School of Medicine, University of Hawaii, Honolulu, Hawaii.
  • Holcombe RF; Cancer Biology Program, University of Hawaii Cancer Center, Honolulu, Hawaii.
  • Jia W; Epidemiology Program, University of Hawaii Cancer Center, Honolulu, Hawaii.
  • Birnbaumer L; Neurobiology Laboratory, National Institute of Environmental Health Sciences, Research Triangle Park, North Carolina; Institute for Biomedical Research (BIOMED), Universidad Católica Argentina, Buenos Aires, Argentina.
  • Zhou X; Department of Gastroenterology, The First Affiliated Hospital of Nanjing Medical University, Nanjing, Jiangsu, China. Electronic address: zhouxiqiao@njmu.edu.cn.
  • Chu WM; Cancer Biology Program, University of Hawaii Cancer Center, Honolulu, Hawaii; The Second Affiliated Hospital, The State Key Laboratory of Respiratory Disease, Guangdong Provincial Key Laboratory of Allergy and Clinical Immunology, Guangzhou Medical University, Guangzhou, Guangdong, China. Electronic
Gastroenterology ; 156(8): 2297-2312, 2019 06.
Article em En | MEDLINE | ID: mdl-30836096
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transformação Celular Neoplásica / Colite / Neoplasias do Colo / Subunidades alfa Gi-Go de Proteínas de Ligação ao GTP Tipo de estudo: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Limite: Animals Idioma: En Revista: Gastroenterology Ano de publicação: 2019 Tipo de documento: Article País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transformação Celular Neoplásica / Colite / Neoplasias do Colo / Subunidades alfa Gi-Go de Proteínas de Ligação ao GTP Tipo de estudo: Diagnostic_studies / Prognostic_studies / Risk_factors_studies Limite: Animals Idioma: En Revista: Gastroenterology Ano de publicação: 2019 Tipo de documento: Article País de publicação: Estados Unidos