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Identification, design and synthesis of novel pyrazolopyridine influenza virus nonstructural protein 1 antagonists.
Patnaik, Samarjit; Basu, Dipanwita; Southall, Noel; Dehdashti, Seameen; Wan, Kanny K; Zheng, Wei; Ferrer, Marc; Taylor, Mercedes; Engel, Daniel A; Marugan, Juan Jose.
Afiliação
  • Patnaik S; Division of Pre-Clinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Rockville, MD 20850, United States. Electronic address: patnaiks@mail.nih.gov.
  • Basu D; Department of Microbiology, Immunology and Cancer Biology, University of Virginia School of Medicine, 1300 Jefferson Park Ave., Charlottesville, VA 22908, United States.
  • Southall N; Division of Pre-Clinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Rockville, MD 20850, United States.
  • Dehdashti S; Division of Pre-Clinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Rockville, MD 20850, United States.
  • Wan KK; Division of Pre-Clinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Rockville, MD 20850, United States.
  • Zheng W; Division of Pre-Clinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Rockville, MD 20850, United States.
  • Ferrer M; Division of Pre-Clinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Rockville, MD 20850, United States.
  • Taylor M; Division of Pre-Clinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Rockville, MD 20850, United States.
  • Engel DA; Alexander BioDiscoveries, LLC, 530 Forrest Rd., Charlottesville, VA 22902, United States. Electronic address: dae2s@virginia.edu.
  • Marugan JJ; Division of Pre-Clinical Innovation, National Center for Advancing Translational Sciences, National Institutes of Health, 9800 Medical Center Drive, Rockville, MD 20850, United States. Electronic address: maruganj@mail.nih.gov.
Bioorg Med Chem Lett ; 29(9): 1113-1119, 2019 05 01.
Article em En | MEDLINE | ID: mdl-30852083
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / Vírus da Influenza A / Pirazóis / Piridinas / Desenho de Fármacos / Proteínas não Estruturais Virais Tipo de estudo: Diagnostic_studies Limite: Animals / Humans / Male Idioma: En Revista: Bioorg Med Chem Lett Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2019 Tipo de documento: Article País de publicação: Reino Unido
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Antivirais / Vírus da Influenza A / Pirazóis / Piridinas / Desenho de Fármacos / Proteínas não Estruturais Virais Tipo de estudo: Diagnostic_studies Limite: Animals / Humans / Male Idioma: En Revista: Bioorg Med Chem Lett Assunto da revista: BIOQUIMICA / QUIMICA Ano de publicação: 2019 Tipo de documento: Article País de publicação: Reino Unido