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MAP4K4 Inhibition Promotes Survival of Human Stem Cell-Derived Cardiomyocytes and Reduces Infarct Size In Vivo.
Fiedler, Lorna R; Chapman, Kathryn; Xie, Min; Maifoshie, Evie; Jenkins, Micaela; Golforoush, Pelin Arabacilar; Bellahcene, Mohamed; Noseda, Michela; Faust, Dörte; Jarvis, Ashley; Newton, Gary; Paiva, Marta Abreu; Harada, Mutsuo; Stuckey, Daniel J; Song, Weihua; Habib, Josef; Narasimhan, Priyanka; Aqil, Rehan; Sanmugalingam, Devika; Yan, Robert; Pavanello, Lorenzo; Sano, Motoaki; Wang, Sam C; Sampson, Robert D; Kanayaganam, Sunthar; Taffet, George E; Michael, Lloyd H; Entman, Mark L; Tan, Tse-Hua; Harding, Sian E; Low, Caroline M R; Tralau-Stewart, Catherine; Perrior, Trevor; Schneider, Michael D.
Afiliação
  • Fiedler LR; British Heart Foundation Centre of Research Excellence, National Heart and Lung Institute, Imperial College London, London W12 0NN, UK.
  • Chapman K; Drug Discovery Centre, Department of Medicine, Imperial College London, London SW7 2AZ, UK; Department of Surgery and Cancer, Imperial College London, London W12 0NN, UK; Domainex, Chesterford Research Park, Little Chesterford, Saffron Walden, Essex CB10 1XL, UK.
  • Xie M; Michael E. DeBakey Heart Center, Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA.
  • Maifoshie E; British Heart Foundation Centre of Research Excellence, National Heart and Lung Institute, Imperial College London, London W12 0NN, UK.
  • Jenkins M; British Heart Foundation Centre of Research Excellence, National Heart and Lung Institute, Imperial College London, London W12 0NN, UK.
  • Golforoush PA; British Heart Foundation Centre of Research Excellence, National Heart and Lung Institute, Imperial College London, London W12 0NN, UK.
  • Bellahcene M; British Heart Foundation Centre of Research Excellence, National Heart and Lung Institute, Imperial College London, London W12 0NN, UK.
  • Noseda M; British Heart Foundation Centre of Research Excellence, National Heart and Lung Institute, Imperial College London, London W12 0NN, UK.
  • Faust D; British Heart Foundation Centre of Research Excellence, National Heart and Lung Institute, Imperial College London, London W12 0NN, UK.
  • Jarvis A; Domainex, Chesterford Research Park, Little Chesterford, Saffron Walden, Essex CB10 1XL, UK.
  • Newton G; Domainex, Chesterford Research Park, Little Chesterford, Saffron Walden, Essex CB10 1XL, UK.
  • Paiva MA; British Heart Foundation Centre of Research Excellence, National Heart and Lung Institute, Imperial College London, London W12 0NN, UK.
  • Harada M; British Heart Foundation Centre of Research Excellence, National Heart and Lung Institute, Imperial College London, London W12 0NN, UK.
  • Stuckey DJ; British Heart Foundation Centre of Research Excellence, National Heart and Lung Institute, Imperial College London, London W12 0NN, UK.
  • Song W; British Heart Foundation Centre of Research Excellence, National Heart and Lung Institute, Imperial College London, London W12 0NN, UK.
  • Habib J; British Heart Foundation Centre of Research Excellence, National Heart and Lung Institute, Imperial College London, London W12 0NN, UK.
  • Narasimhan P; Domainex, Chesterford Research Park, Little Chesterford, Saffron Walden, Essex CB10 1XL, UK.
  • Aqil R; Domainex, Chesterford Research Park, Little Chesterford, Saffron Walden, Essex CB10 1XL, UK.
  • Sanmugalingam D; Domainex, Chesterford Research Park, Little Chesterford, Saffron Walden, Essex CB10 1XL, UK.
  • Yan R; Domainex, Chesterford Research Park, Little Chesterford, Saffron Walden, Essex CB10 1XL, UK.
  • Pavanello L; Domainex, Chesterford Research Park, Little Chesterford, Saffron Walden, Essex CB10 1XL, UK.
  • Sano M; Michael E. DeBakey Heart Center, Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA.
  • Wang SC; Michael E. DeBakey Heart Center, Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA.
  • Sampson RD; British Heart Foundation Centre of Research Excellence, National Heart and Lung Institute, Imperial College London, London W12 0NN, UK.
  • Kanayaganam S; British Heart Foundation Centre of Research Excellence, National Heart and Lung Institute, Imperial College London, London W12 0NN, UK.
  • Taffet GE; Michael E. DeBakey Heart Center, Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA.
  • Michael LH; Michael E. DeBakey Heart Center, Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA.
  • Entman ML; Michael E. DeBakey Heart Center, Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA.
  • Tan TH; Immunology Research Center, National Health Research Institutes, Zhunan 35053, Taiwan; Department of Pathology and Immunology, Baylor College of Medicine, Houston, TX 77030, USA.
  • Harding SE; British Heart Foundation Centre of Research Excellence, National Heart and Lung Institute, Imperial College London, London W12 0NN, UK.
  • Low CMR; Drug Discovery Centre, Department of Medicine, Imperial College London, London SW7 2AZ, UK.
  • Tralau-Stewart C; Drug Discovery Centre, Department of Medicine, Imperial College London, London SW7 2AZ, UK.
  • Perrior T; Domainex, Chesterford Research Park, Little Chesterford, Saffron Walden, Essex CB10 1XL, UK.
  • Schneider MD; British Heart Foundation Centre of Research Excellence, National Heart and Lung Institute, Imperial College London, London W12 0NN, UK; Michael E. DeBakey Heart Center, Department of Medicine, Baylor College of Medicine, Houston, TX 77030, USA. Electronic address: m.d.schneider@imperial.ac.uk.
Cell Stem Cell ; 24(4): 579-591.e12, 2019 04 04.
Article em En | MEDLINE | ID: mdl-30853557
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doxorrubicina / Proteínas Serina-Treonina Quinases / Miócitos Cardíacos / Peptídeos e Proteínas de Sinalização Intracelular / Infarto Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Revista: Cell Stem Cell Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Doxorrubicina / Proteínas Serina-Treonina Quinases / Miócitos Cardíacos / Peptídeos e Proteínas de Sinalização Intracelular / Infarto Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans / Male Idioma: En Revista: Cell Stem Cell Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Estados Unidos