Attenuation of the effects of oxidative stress by the MAO-inhibiting antidepressant and carbonyl scavenger phenelzine.

Baker, Glen; Matveychuk, Dmitriy; MacKenzie, Erin M; Holt, Andrew; Wang, Yanlin; Kar, Satyabrata

Baker, Glen; Matveychuk, Dmitriy; MacKenzie, Erin M; Holt, Andrew; Wang, Yanlin; Kar, Satyabrata.

Afiliação

Baker G; Department of Psychiatry (Neurochemical Research Unit), University of Alberta, Edmonton, Canada. Electronic address: glen.baker@ualberta.ca.
Matveychuk D; Department of Psychiatry (Neurochemical Research Unit), University of Alberta, Edmonton, Canada. Electronic address: dmitriym@ualberta.ca.
MacKenzie EM; Department of Psychiatry (Neurochemical Research Unit), University of Alberta, Edmonton, Canada. Electronic address: emm3@ualberta.ca.
Holt A; Department of Psychiatry (Neurochemical Research Unit), University of Alberta, Edmonton, Canada. Electronic address: aholt@ualberta.ca.
Wang Y; Department of Psychiatry (Neurochemical Research Unit), University of Alberta, Edmonton, Canada; Department of Medicine (Neurology), University of Alberta, Edmonton, Canada. Electronic address: yanlin.wang8@gmail.com.
Kar S; Department of Psychiatry (Neurochemical Research Unit), University of Alberta, Edmonton, Canada; Department of Medicine (Neurology), University of Alberta, Edmonton, Canada. Electronic address: skar@ualberta.ca.

Chem Biol Interact ; 304: 139-147, 2019 May 01.

Article em En | MEDLINE | ID: mdl-30857888

Assuntos

Antidepressivos/farmacologia; Sequestradores de Radicais Livres/farmacologia; Inibidores da Monoaminoxidase/farmacologia; Monoaminoxidase/metabolismo; Estresse Oxidativo/efeitos dos fármacos; Fenelzina/farmacologia; Animais; Antidepressivos/química; Sequestradores de Radicais Livres/química; Humanos; Estrutura Molecular; Inibidores da Monoaminoxidase/química; Fenelzina/química

Palavras-chave

Antidepressant; GABA transaminase; Monoamine oxidase; Phenelzine; Primary amine oxidase; Reactive aldehydes

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fenelzina / Sequestradores de Radicais Livres / Estresse Oxidativo / Monoaminoxidase / Inibidores da Monoaminoxidase / Antidepressivos Limite: Animals / Humans Idioma: En Revista: Chem Biol Interact Ano de publicação: 2019 Tipo de documento: Article País de publicação: Irlanda

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