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Therapeutic efficacy, pharmacokinetic profiles, and toxicological activities of humanized antibody-drug conjugate Zt/g4-MMAE targeting RON receptor tyrosine kinase for cancer therapy.
Yao, Hang-Ping; Feng, Liang; Suthe, Sreedhar Reddy; Chen, Ling-Hui; Weng, Tian-Hao; Hu, Chen-Yu; Jun, Eun Sung; Wu, Zhi-Gang; Wang, Wei-Lin; Kim, Song Cheol; Tong, Xiang-Min; Wang, Ming-Hai.
Afiliação
  • Yao HP; State Key Laboratory for Diagnosis & Treatment of Infectious Diseases, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
  • Feng L; Cancer Biology Research Center, Hangzhou, China.
  • Suthe SR; Department of Pharmaceutical Sciences, Texas Tech University Health Sciences Center School of Pharmacy, Amarillo, TX, USA.
  • Chen LH; Department of Pharmaceutical Sciences, Texas Tech University Health Sciences Center School of Pharmacy, Amarillo, TX, USA.
  • Weng TH; Zhejiang Provincial Key Laboratory for Precision Diagnosis & Treatment of Hepatic & Pancreatic Oncology, Zhejiang Province, China.
  • Hu CY; Division of Hepatobiliary & Pancreatic Surgery, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
  • Jun ES; State Key Laboratory for Diagnosis & Treatment of Infectious Diseases, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
  • Wu ZG; State Key Laboratory for Diagnosis & Treatment of Infectious Diseases, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China.
  • Wang WL; Department of Biomedical Sciences, Kowloon Tong, Hong Kong.
  • Kim SC; Zhejiang Provincial Key Laboratory for Precision Diagnosis & Treatment of Hepatic & Pancreatic Oncology, Zhejiang Province, China.
  • Tong XM; Zhejiang Provincial Key Laboratory for Precision Diagnosis & Treatment of Hepatic & Pancreatic Oncology, Zhejiang Province, China. wam@zju.edu.cn.
  • Wang MH; Division of Hepatobiliary & Pancreatic Surgery, First Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, China. wam@zju.edu.cn.
J Immunother Cancer ; 7(1): 75, 2019 03 14.
Article em En | MEDLINE | ID: mdl-30871619
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oligopeptídeos / Neoplasias Pancreáticas / Receptores Proteína Tirosina Quinases / Imunoconjugados / Carcinoma Ductal Pancreático / Anticorpos Monoclonais Humanizados Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: J Immunother Cancer Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China País de publicação: Reino Unido
Texto completo
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XML
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Oligopeptídeos / Neoplasias Pancreáticas / Receptores Proteína Tirosina Quinases / Imunoconjugados / Carcinoma Ductal Pancreático / Anticorpos Monoclonais Humanizados Tipo de estudo: Prognostic_studies Limite: Animals / Female / Humans Idioma: En Revista: J Immunother Cancer Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China País de publicação: Reino Unido