2'-Hydroxy-5'-methoxyacetophenone attenuates the inflammatory response in LPS-induced BV-2 and RAW264.7 cells via NF-&#954;B signaling pathway.

Zhang, YuanYuan; Li, ChengYong; Zhou, ChunXia; Hong, PengZhi; Zhang, Yi; Sun, ShengLi; Qian, Zhong-Ji

2'-Hydroxy-5'-methoxyacetophenone attenuates the inflammatory response in LPS-induced BV-2 and RAW264.7 cells via NF-κB signaling pathway.

Zhang, YuanYuan; Li, ChengYong; Zhou, ChunXia; Hong, PengZhi; Zhang, Yi; Sun, ShengLi; Qian, Zhong-Ji.

Afiliação

Zhang Y; School of Chemistry and Environment of Chemistry and Environment, Guangdong Ocean University, Zhanjiang 524088, China; College of Food Science and Technology, Guangdong Ocean University, Zhanjiang 524088, China.
Li C; School of Chemistry and Environment of Chemistry and Environment, Guangdong Ocean University, Zhanjiang 524088, China; Shenzhen Institute of Guangdong Ocean University, Shenzhen 518108, China.
Zhou C; College of Food Science and Technology, Guangdong Ocean University, Zhanjiang 524088, China; Shenzhen Institute of Guangdong Ocean University, Shenzhen 518108, China.
Hong P; College of Food Science and Technology, Guangdong Ocean University, Zhanjiang 524088, China.
Zhang Y; College of Food Science and Technology, Guangdong Ocean University, Zhanjiang 524088, China.
Sun S; School of Chemistry and Environment of Chemistry and Environment, Guangdong Ocean University, Zhanjiang 524088, China.
Qian ZJ; School of Chemistry and Environment of Chemistry and Environment, Guangdong Ocean University, Zhanjiang 524088, China; Shenzhen Institute of Guangdong Ocean University, Shenzhen 518108, China. Electronic address: zjqian78@163.com.

J Neuroimmunol ; 330: 143-151, 2019 05 15.

Article em En | MEDLINE | ID: mdl-30884275

Assuntos

Anti-Inflamatórios/farmacologia; Mediadores da Inflamação/metabolismo; Lipopolissacarídeos/toxicidade; NF-kappa B/metabolismo; Transdução de Sinais/efeitos dos fármacos; Animais; Anti-Inflamatórios/isolamento & purificação; Relação Dose-Resposta a Droga; Mediadores da Inflamação/antagonistas & inibidores; Camundongos; NF-kappa B/antagonistas & inibidores; Células RAW 264.7; Espécies Reativas de Oxigênio/antagonistas & inibidores; Espécies Reativas de Oxigênio/metabolismo; Transdução de Sinais/fisiologia; Smegmamorpha

Palavras-chave

2'-Hydroxy-5'-Methoxyacetophenone; Anti-inflammation; Hippocampus kuda; Molecular docking; NF-Κb

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transdução de Sinais / Lipopolissacarídeos / NF-kappa B / Mediadores da Inflamação / Anti-Inflamatórios Limite: Animals Idioma: En Revista: J Neuroimmunol Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China País de publicação: Holanda

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