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Variation in the Plasma Membrane Monoamine Transporter (PMAT) (Encoded by SLC29A4) and Organic Cation Transporter 1 (OCT1) (Encoded by SLC22A1) and Gastrointestinal Intolerance to Metformin in Type 2 Diabetes: An IMI DIRECT Study.
Dawed, Adem Y; Zhou, Kaixin; van Leeuwen, Nienke; Mahajan, Anubha; Robertson, Neil; Koivula, Robert; Elders, Petra J M; Rauh, Simone P; Jones, Angus G; Holl, Reinhard W; Stingl, Julia C; Franks, Paul W; McCarthy, Mark I; 't Hart, Leen M; Pearson, Ewan R.
Afiliação
  • Dawed AY; Division of Population Health and Genomics, School of Medicine, University of Dundee, Dundee, U.K.
  • Zhou K; Division of Population Health and Genomics, School of Medicine, University of Dundee, Dundee, U.K.
  • van Leeuwen N; Cell and Chemical Biology, Leiden University Medical Center, Leiden, the Netherlands.
  • Mahajan A; Wellcome Centre for Human Genetics, University of Oxford, Oxford, U.K.
  • Robertson N; Wellcome Centre for Human Genetics, University of Oxford, Oxford, U.K.
  • Koivula R; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, U.K.
  • Elders PJM; Oxford Centre for Diabetes, Endocrinology and Metabolism, Radcliffe Department of Medicine, University of Oxford, Oxford, U.K.
  • Rauh SP; Genetic and Molecular Epidemiology Unit, Department of Clinical Sciences, Skåne University Hospital, Malmö, Lund University, Malmö, Sweden.
  • Jones AG; Department of General Practice and Elderly Care Medicine, Amsterdam Public Health Research Institute, Amsterdam University Medical Center, Amsterdam, the Netherlands.
  • Holl RW; Department of Epidemiology and Biostatistics, Amsterdam Public Health Research Institute, Amsterdam University Medical Center, Amsterdam, the Netherlands.
  • Stingl JC; Institute of Clinical and Biological Sciences, University of Exeter Medical School, Exeter, U.K.
  • Franks PW; Institute of Epidemiology and Medical Biometry (ZIBMT), University of Ulm, Ulm, Germany, and German Center for Diabetes Research (DZD), München-Neuherberg, Germany.
  • McCarthy MI; Research Division, Federal Institute for Drugs and Medical Devices, Bonn, Germany.
  • 't Hart LM; Genetic and Molecular Epidemiology Unit, Department of Clinical Sciences, Skåne University Hospital, Malmö, Lund University, Malmö, Sweden.
  • Pearson ER; Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.
Diabetes Care ; 42(6): 1027-1033, 2019 06.
Article em En | MEDLINE | ID: mdl-30885951
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transportador 1 de Cátions Orgânicos / Proteínas de Transporte de Nucleosídeo Equilibrativas / Diabetes Mellitus Tipo 2 / Hipersensibilidade a Drogas / Gastroenteropatias / Metformina Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Diabetes Care Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Transportador 1 de Cátions Orgânicos / Proteínas de Transporte de Nucleosídeo Equilibrativas / Diabetes Mellitus Tipo 2 / Hipersensibilidade a Drogas / Gastroenteropatias / Metformina Tipo de estudo: Etiology_studies / Prognostic_studies / Risk_factors_studies Limite: Aged / Female / Humans / Male / Middle aged Idioma: En Revista: Diabetes Care Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Reino Unido País de publicação: Estados Unidos