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Discovery of common chemical exposures across three continents using silicone wristbands.
Dixon, Holly M; Armstrong, Georgina; Barton, Michael; Bergmann, Alan J; Bondy, Melissa; Halbleib, Mary L; Hamilton, Winifred; Haynes, Erin; Herbstman, Julie; Hoffman, Peter; Jepson, Paul; Kile, Molly L; Kincl, Laurel; Laurienti, Paul J; North, Paula; Paulik, L Blair; Petrosino, Joe; Points, Gary L; Poutasse, Carolyn M; Rohlman, Diana; Scott, Richard P; Smith, Brian; Tidwell, Lane G; Walker, Cheryl; Waters, Katrina M; Anderson, Kim A.
Afiliação
  • Dixon HM; Food Safety and Environmental Stewardship Program, Environmental and Molecular Toxicology, Oregon State University, Corvallis, OR, USA.
  • Armstrong G; Department of Medicine, Section of Epidemiology and Population Sciences, Baylor College of Medicine, Houston, TX, USA.
  • Barton M; Food Safety and Environmental Stewardship Program, Environmental and Molecular Toxicology, Oregon State University, Corvallis, OR, USA.
  • Bergmann AJ; Food Safety and Environmental Stewardship Program, Environmental and Molecular Toxicology, Oregon State University, Corvallis, OR, USA.
  • Bondy M; Department of Medicine, Section of Epidemiology and Population Sciences, Baylor College of Medicine, Houston, TX, USA.
  • Halbleib ML; Department of Crop and Soil Science, Oregon State University, Corvallis, OR, USA.
  • Hamilton W; Department of Medicine, Environmental Health Section, Baylor College of Medicine, Houston, TX, USA.
  • Haynes E; College of Medicine, Department of Environmental Health, University of Cincinnati, Cincinnati, OH, USA.
  • Herbstman J; Columbia Center for Children's Environmental Health, Department of Environmental Health Sciences, Mailman School of Public Health, Columbia University, New York, NY, USA.
  • Hoffman P; Food Safety and Environmental Stewardship Program, Environmental and Molecular Toxicology, Oregon State University, Corvallis, OR, USA.
  • Jepson P; Integrated Plant Protection Center, Oregon State University, Corvallis, OR, USA.
  • Kile ML; College of Public Health and Human Sciences, Oregon State University, Corvallis, OR, USA.
  • Kincl L; College of Public Health and Human Sciences, Oregon State University, Corvallis, OR, USA.
  • Laurienti PJ; Department of Radiology, Wake Forest School of Medicine, Winston-Salem, NC, USA.
  • North P; Department of Pathology, Medical College of Wisconsin, Milwaukee, WI, USA.
  • Paulik LB; Food Safety and Environmental Stewardship Program, Environmental and Molecular Toxicology, Oregon State University, Corvallis, OR, USA.
  • Petrosino J; Department of Molecular Virology and Microbiology, Baylor College of Medicine, Houston, TX, USA.
  • Points GL; Food Safety and Environmental Stewardship Program, Environmental and Molecular Toxicology, Oregon State University, Corvallis, OR, USA.
  • Poutasse CM; Food Safety and Environmental Stewardship Program, Environmental and Molecular Toxicology, Oregon State University, Corvallis, OR, USA.
  • Rohlman D; College of Public Health and Human Sciences, Oregon State University, Corvallis, OR, USA.
  • Scott RP; Food Safety and Environmental Stewardship Program, Environmental and Molecular Toxicology, Oregon State University, Corvallis, OR, USA.
  • Smith B; Food Safety and Environmental Stewardship Program, Environmental and Molecular Toxicology, Oregon State University, Corvallis, OR, USA.
  • Tidwell LG; Food Safety and Environmental Stewardship Program, Environmental and Molecular Toxicology, Oregon State University, Corvallis, OR, USA.
  • Walker C; Department of Medicine, Center for Precision Environmental Health, Baylor College of Medicine, Houston, TX, USA.
  • Waters KM; Biological Sciences Division, Pacific Northwest National Laboratory, Richland, WA, USA.
  • Anderson KA; Food Safety and Environmental Stewardship Program, Environmental and Molecular Toxicology, Oregon State University, Corvallis, OR, USA.
R Soc Open Sci ; 6(2): 181836, 2019 Feb.
Article em En | MEDLINE | ID: mdl-30891293
ABSTRACT
To assess differences and trends in personal chemical exposure, volunteers from 14 communities in Africa (Senegal, South Africa), North America (United States (U.S.)) and South America (Peru) wore 262 silicone wristbands. We analysed wristband extracts for 1530 unique chemicals, resulting in 400 860 chemical data points. The number of chemical detections ranged from 4 to 43 per wristband, with 191 different chemicals detected, and 1339 chemicals were not detected in any wristband. No two wristbands had identical chemical detections. We detected 13 potential endocrine disrupting chemicals in over 50% of all wristbands and found 36 chemicals in common between chemicals detected in three geographical wristband groups (Africa, North America and South America). U.S. children (less than or equal to 11 years) had the highest percentage of flame retardant detections compared with all other participants. Wristbands worn in Texas post-Hurricane Harvey had the highest mean number of chemical detections (28) compared with other study locations (10-25). Consumer product-related chemicals and phthalates were a high percentage of chemical detections across all study locations (36-53% and 18-42%, respectively). Chemical exposures varied among individuals; however, many individuals were exposed to similar chemical mixtures. Our exploratory investigation uncovered personal chemical exposure trends that can help prioritize certain mixtures and chemical classes for future studies.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: R Soc Open Sci Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Idioma: En Revista: R Soc Open Sci Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos