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Highly efficient therapeutic gene editing of human hematopoietic stem cells.
Wu, Yuxuan; Zeng, Jing; Roscoe, Benjamin P; Liu, Pengpeng; Yao, Qiuming; Lazzarotto, Cicera R; Clement, Kendell; Cole, Mitchel A; Luk, Kevin; Baricordi, Cristina; Shen, Anne H; Ren, Chunyan; Esrick, Erica B; Manis, John P; Dorfman, David M; Williams, David A; Biffi, Alessandra; Brugnara, Carlo; Biasco, Luca; Brendel, Christian; Pinello, Luca; Tsai, Shengdar Q; Wolfe, Scot A; Bauer, Daniel E.
Afiliação
  • Wu Y; Division of Hematology/Oncology, Boston Children's Hospital , Boston, MA, USA.
  • Zeng J; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Roscoe BP; Department of Pediatrics, Harvard Stem Cell Institute, Broad Institute of Harvard and MIT, Harvard Medical School, Boston, MA, USA.
  • Liu P; Shanghai Key Laboratory of Regulatory Biology, Institute of Biomedical Sciences and School of Life Sciences, East China Normal University, Shanghai, China.
  • Yao Q; Division of Hematology/Oncology, Boston Children's Hospital , Boston, MA, USA.
  • Lazzarotto CR; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Clement K; Department of Pediatrics, Harvard Stem Cell Institute, Broad Institute of Harvard and MIT, Harvard Medical School, Boston, MA, USA.
  • Cole MA; Department of Molecular, Cell and Cancer Biology, Li Weibo Institute for Rare Diseases Research, University of Massachusetts Medical School, Worcester, MA, USA.
  • Luk K; Department of Molecular, Cell and Cancer Biology, Li Weibo Institute for Rare Diseases Research, University of Massachusetts Medical School, Worcester, MA, USA.
  • Baricordi C; Division of Hematology/Oncology, Boston Children's Hospital , Boston, MA, USA.
  • Shen AH; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Ren C; Department of Pediatrics, Harvard Stem Cell Institute, Broad Institute of Harvard and MIT, Harvard Medical School, Boston, MA, USA.
  • Esrick EB; Molecular Pathology Unit, Center for Cancer Research, and Center for Computational and Integrative Biology, Massachusetts General Hospital, Boston, MA, USA.
  • Manis JP; Department of Pathology, Broad Institute of Harvard and MIT, Harvard Medical School, Boston, MA, USA.
  • Dorfman DM; Department of Hematology, St. Jude Children's Research Hospital, Memphis, TN, USA.
  • Williams DA; Molecular Pathology Unit, Center for Cancer Research, and Center for Computational and Integrative Biology, Massachusetts General Hospital, Boston, MA, USA.
  • Biffi A; Department of Pathology, Broad Institute of Harvard and MIT, Harvard Medical School, Boston, MA, USA.
  • Brugnara C; Division of Hematology/Oncology, Boston Children's Hospital , Boston, MA, USA.
  • Biasco L; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Brendel C; Department of Pediatrics, Harvard Stem Cell Institute, Broad Institute of Harvard and MIT, Harvard Medical School, Boston, MA, USA.
  • Pinello L; Department of Molecular, Cell and Cancer Biology, Li Weibo Institute for Rare Diseases Research, University of Massachusetts Medical School, Worcester, MA, USA.
  • Tsai SQ; Division of Hematology/Oncology, Boston Children's Hospital , Boston, MA, USA.
  • Wolfe SA; Department of Pediatric Oncology, Dana-Farber Cancer Institute, Boston, MA, USA.
  • Bauer DE; Department of Pediatrics, Harvard Stem Cell Institute, Broad Institute of Harvard and MIT, Harvard Medical School, Boston, MA, USA.
Nat Med ; 25(5): 776-783, 2019 05.
Article em En | MEDLINE | ID: mdl-30911135

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células-Tronco Hematopoéticas / Edição de Genes Limite: Humans Idioma: En Revista: Nat Med Assunto da revista: BIOLOGIA MOLECULAR / MEDICINA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células-Tronco Hematopoéticas / Edição de Genes Limite: Humans Idioma: En Revista: Nat Med Assunto da revista: BIOLOGIA MOLECULAR / MEDICINA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos