Disruption of Telomerase RNA Maturation Kinetics Precipitates Disease.

Roake, Caitlin M; Chen, Lu; Chakravarthy, Ananya L; Ferrell, James E; Raffa, Grazia D; Artandi, Steven E

Roake, Caitlin M; Chen, Lu; Chakravarthy, Ananya L; Ferrell, James E; Raffa, Grazia D; Artandi, Steven E.

Afiliação

Roake CM; Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Biochemistry, Stanford University School of Medicine, Stanford, CA 94305, USA.
Chen L; Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Biochemistry, Stanford University School of Medicine, Stanford, CA 94305, USA.
Chakravarthy AL; Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Biochemistry, Stanford University School of Medicine, Stanford, CA 94305, USA.
Ferrell JE; Department of Biochemistry, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Chemical and Systems Biology, Stanford, CA 94305, USA.
Raffa GD; Dipartimento di Biologia e Biotecnologie, Sapienza University of Rome, Rome, Italy.
Artandi SE; Stanford Cancer Institute, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Medicine, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Biochemistry, Stanford University School of Medicine, Stanford, CA 94305, USA. Electronic address: sartan

Mol Cell ; 74(4): 688-700.e3, 2019 05 16.

Article em En | MEDLINE | ID: mdl-30930056

Assuntos

Disceratose Congênita/genética; Exorribonucleases/genética; RNA Nucleotidiltransferases/genética; RNA/genética; Telomerase/genética; Disceratose Congênita/patologia; Mutação em Linhagem Germinativa/genética; Células HeLa; Humanos; Cinética; Processamento Pós-Transcricional do RNA/genética

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: RNA Nucleotidiltransferases / RNA / Telomerase / Disceratose Congênita / Exorribonucleases Limite: Humans Idioma: En Revista: Mol Cell Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Estados Unidos

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