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Platelet GPIbα is a mediator and potential interventional target for NASH and subsequent liver cancer.
Malehmir, Mohsen; Pfister, Dominik; Gallage, Suchira; Szydlowska, Marta; Inverso, Donato; Kotsiliti, Elena; Leone, Valentina; Peiseler, Moritz; Surewaard, Bas G J; Rath, Dominik; Ali, Adnan; Wolf, Monika Julia; Drescher, Hannah; Healy, Marc E; Dauch, Daniel; Kroy, Daniela; Krenkel, Oliver; Kohlhepp, Marlene; Engleitner, Thomas; Olkus, Alexander; Sijmonsma, Tjeerd; Volz, Julia; Deppermann, Carsten; Stegner, David; Helbling, Patrick; Nombela-Arrieta, César; Rafiei, Anahita; Hinterleitner, Martina; Rall, Marcel; Baku, Florian; Borst, Oliver; Wilson, Caroline L; Leslie, Jack; O'Connor, Tracy; Weston, Christopher J; Chauhan, Abhishek; Adams, David H; Sheriff, Lozan; Teijeiro, Ana; Prinz, Marco; Bogeska, Ruzhica; Anstee, Natasha; Bongers, Malte N; Notohamiprodjo, Mike; Geisler, Tobias; Withers, Dominic J; Ware, Jerry; Mann, Derek A; Augustin, Hellmut G; Vegiopoulos, Alexandros.
Afiliação
  • Malehmir M; Department of Pathology and Molecular Pathology, University and University Hospital Zurich, Zurich, Switzerland.
  • Pfister D; Division of Chronic Inflammation and Cancer, German Cancer Research Center Heidelberg (DKFZ), Heidelberg, Germany.
  • Gallage S; Division of Chronic Inflammation and Cancer, German Cancer Research Center Heidelberg (DKFZ), Heidelberg, Germany.
  • Szydlowska M; Division of Chronic Inflammation and Cancer, German Cancer Research Center Heidelberg (DKFZ), Heidelberg, Germany.
  • Inverso D; Division of Vascular Oncology and Metastasis, German Cancer Research Center Heidelberg (DKFZ-ZMBH Alliance), Heidelberg, Germany.
  • Kotsiliti E; European Center of Angioscience (ECAS), Medical Faculty Mannheim, Heidelberg University, Mannheim, Germany.
  • Leone V; Division of Chronic Inflammation and Cancer, German Cancer Research Center Heidelberg (DKFZ), Heidelberg, Germany.
  • Peiseler M; Institute for Virology, Technische Universität München/Helmholtz Zentrum München, Munich, Germany.
  • Surewaard BGJ; Division of Chronic Inflammation and Cancer, German Cancer Research Center Heidelberg (DKFZ), Heidelberg, Germany.
  • Rath D; Research Unit of Radiation Cytogenetics, Helmholtz Zentrum München, Neuherberg, Germany.
  • Ali A; Calvin Phoebe & Joan Snyder Institute for Chronic Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
  • Wolf MJ; Department of Physiology and Pharmacology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
  • Drescher H; Department of Physiology and Pharmacology, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
  • Healy ME; Department of Microbiology, Immunology & Infectious Diseases, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
  • Dauch D; Department of Medical Microbiology, University Medical Center, Utrmeecht, the Netherlands.
  • Kroy D; Department of Cardiology and Circulatory Diseases, Internal Medicine Clinic III, Eberhard Karls University Tübingen, Tübingen, Germany.
  • Krenkel O; Division of Chronic Inflammation and Cancer, German Cancer Research Center Heidelberg (DKFZ), Heidelberg, Germany.
  • Kohlhepp M; Department of Pathology and Molecular Pathology, University and University Hospital Zurich, Zurich, Switzerland.
  • Engleitner T; Department of Medicine III, University Hospital RWTH Aachen, Aachen, Germany.
  • Olkus A; Department of Pathology and Molecular Pathology, University and University Hospital Zurich, Zurich, Switzerland.
  • Sijmonsma T; Department of Internal Medicine VIII, University Hospital Tübingen, Tübingen, Germany.
  • Volz J; Department of Physiology I, Institute of Physiology, Eberhard Karls University Tübingen, Tübingen, Germany.
  • Deppermann C; Department of Medicine III, University Hospital RWTH Aachen, Aachen, Germany.
  • Stegner D; Department of Medicine III, University Hospital RWTH Aachen, Aachen, Germany.
  • Helbling P; Department of Medicine III, University Hospital RWTH Aachen, Aachen, Germany.
  • Nombela-Arrieta C; Center for Translational Cancer Research (TranslaTUM), Technische Universität München, Munich, Germany.
  • Rafiei A; Department of Medicine II, Klinikum Rechts der Isar, Technische Universität München, Munich, Germany.
  • Hinterleitner M; German Cancer Consortium (DKTK), German Cancer Research Center (DKFZ), Heidelberg, Germany.
  • Rall M; Division of Chronic Inflammation and Cancer, German Cancer Research Center Heidelberg (DKFZ), Heidelberg, Germany.
  • Baku F; Medical Faculty, University of Heidelberg, Heidelberg, Germany.
  • Borst O; Division of Chronic Inflammation and Cancer, German Cancer Research Center Heidelberg (DKFZ), Heidelberg, Germany.
  • Wilson CL; Institute of Experimental Biomedicine, University Hospital and Rudolf Virchow Center, University of Würzburg, Würzburg, Germany.
  • Leslie J; Institute of Experimental Biomedicine, University Hospital and Rudolf Virchow Center, University of Würzburg, Würzburg, Germany.
  • O'Connor T; Institute of Experimental Biomedicine, University Hospital and Rudolf Virchow Center, University of Würzburg, Würzburg, Germany.
  • Weston CJ; Hematology, University Hospital and University of Zurich, Zurich, Switzerland.
  • Chauhan A; Hematology, University Hospital and University of Zurich, Zurich, Switzerland.
  • Adams DH; Hematology, University Hospital and University of Zurich, Zurich, Switzerland.
  • Sheriff L; Department of Internal Medicine VIII, University Hospital Tübingen, Tübingen, Germany.
  • Teijeiro A; Department of Physiology I, Institute of Physiology, Eberhard Karls University Tübingen, Tübingen, Germany.
  • Prinz M; Department of Cardiology and Circulatory Diseases, Internal Medicine Clinic III, Eberhard Karls University Tübingen, Tübingen, Germany.
  • Bogeska R; Department of Cardiology and Circulatory Diseases, Internal Medicine Clinic III, Eberhard Karls University Tübingen, Tübingen, Germany.
  • Anstee N; Department of Cardiology and Circulatory Diseases, Internal Medicine Clinic III, Eberhard Karls University Tübingen, Tübingen, Germany.
  • Bongers MN; Newcastle Fibrosis Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle Upon Tyne, UK.
  • Notohamiprodjo M; Newcastle Fibrosis Research Group, Institute of Cellular Medicine, Newcastle University, Newcastle Upon Tyne, UK.
  • Geisler T; Institute for Virology, Technische Universität München/Helmholtz Zentrum München, Munich, Germany.
  • Withers DJ; Institute of Molecular Immunology and Experimental Oncology, Technical University of Munich, Munich, Germany.
  • Ware J; Centre for Liver Research and National Institute for Health Research (NIHR) Birmingham Liver Biomedical Research Unit, Birmingham, UK.
  • Mann DA; Centre for Liver Research and National Institute for Health Research (NIHR) Birmingham Liver Biomedical Research Unit, Birmingham, UK.
  • Augustin HG; Centre for Liver Research and National Institute for Health Research (NIHR) Birmingham Liver Biomedical Research Unit, Birmingham, UK.
  • Vegiopoulos A; Liver Unit, University Hospitals Birmingham NHS Trust, Birmingham, UK.
Nat Med ; 25(4): 641-655, 2019 04.
Article em En | MEDLINE | ID: mdl-30936549
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Plaquetas / Complexo Glicoproteico GPIb-IX de Plaquetas / Hepatopatia Gordurosa não Alcoólica / Neoplasias Hepáticas Limite: Animals / Humans Idioma: En Revista: Nat Med Assunto da revista: BIOLOGIA MOLECULAR / MEDICINA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Suíça País de publicação: Estados Unidos
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Plaquetas / Complexo Glicoproteico GPIb-IX de Plaquetas / Hepatopatia Gordurosa não Alcoólica / Neoplasias Hepáticas Limite: Animals / Humans Idioma: En Revista: Nat Med Assunto da revista: BIOLOGIA MOLECULAR / MEDICINA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Suíça País de publicação: Estados Unidos