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New flavonoid and stilbene derivatives from the fruits of Macaranga balansae.
Mai, Huong Doan Thi; Toan, Thang Pham; Huu, Giap Tran; Le, Thanh Nguyen; Oanh, Vu Thi Kim; Hang, Nguyen Thi Minh; Thu, Huong Tran; Chau, Van Minh; Litaudon, Marc; Pham, Van Cuong.
Afiliação
  • Mai HDT; Advanced Center for Bioorganic Chemistry, Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST) , Caugiay , Hanoi, Vietnam.
  • Toan TP; Graduate University of Science and Technology, VAST , Caugiay , Hanoi, Vietnam.
  • Huu GT; School of Chemical Engineering, Hanoi University of Science and Technology , Ha Ba Trung , Hanoi, Vietnam.
  • Le TN; Institute of Forensic Sciences, Ministry of Public Security , Thanh Xuan , Hanoi, Vietnam.
  • Oanh VTK; Advanced Center for Bioorganic Chemistry, Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST) , Caugiay , Hanoi, Vietnam.
  • Hang NTM; Advanced Center for Bioorganic Chemistry, Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST) , Caugiay , Hanoi, Vietnam.
  • Thu HT; Graduate University of Science and Technology, VAST , Caugiay , Hanoi, Vietnam.
  • Chau VM; Advanced Center for Bioorganic Chemistry, Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST) , Caugiay , Hanoi, Vietnam.
  • Litaudon M; Advanced Center for Bioorganic Chemistry, Institute of Marine Biochemistry, Vietnam Academy of Science and Technology (VAST) , Caugiay , Hanoi, Vietnam.
  • Pham VC; School of Chemical Engineering, Hanoi University of Science and Technology , Ha Ba Trung , Hanoi, Vietnam.
Nat Prod Res ; 34(19): 2772-2778, 2020 Oct.
Article em En | MEDLINE | ID: mdl-30938172
Two new prenylated flavonoids, 4´-methyl-8-prenyltaxifolin (1) and 6,8-diprenyl-4´-methyl-naringenin (2) and a new geranylated stilbene, 4'-deprenyl-4-methoxymappain (3) together with eight known flavonoids (4-11) were isolated from the fruits of Macaranga balansae Gagnep. Their chemical structures were determined by means of spectroscopic methods including 1D, 2D NMR, and MS data. Compound 2 showed the highest cytotoxic activity against PanC1, A549, KB and LU-1 cell lines with IC50 values range from 7.89 to 22.81 µM.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estilbenos / Flavonoides / Euphorbiaceae / Antineoplásicos Fitogênicos Limite: Humans Idioma: En Revista: Nat Prod Res Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Vietnã País de publicação: Reino Unido
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Estilbenos / Flavonoides / Euphorbiaceae / Antineoplásicos Fitogênicos Limite: Humans Idioma: En Revista: Nat Prod Res Ano de publicação: 2020 Tipo de documento: Article País de afiliação: Vietnã País de publicação: Reino Unido