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Genomic resources for the study of echinoderm development and evolution.
Cary, Gregory A; Cameron, R Andrew; Hinman, Veronica F.
Afiliação
  • Cary GA; Department of Biological Sciences, Carnegie Mellon University, Mellon Institute, Pittsburgh, PA, United States.
  • Cameron RA; Department of Biological Sciences, Carnegie Mellon University, Mellon Institute, Pittsburgh, PA, United States.
  • Hinman VF; Department of Biological Sciences, Carnegie Mellon University, Mellon Institute, Pittsburgh, PA, United States. Electronic address: veronica@cmu.edu.
Methods Cell Biol ; 151: 65-88, 2019.
Article em En | MEDLINE | ID: mdl-30948032
ABSTRACT
Echinoderms are important research models for a wide range of biological questions. In particular, echinoderm embryos are exemplary models for dissecting the molecular and cellular processes that drive development and testing how these processes can be modified through evolution to produce the extensive morphological diversity observed in the phylum. Modern attempts to characterize these processes depend on some level of genomic analysis; from querying annotated gene sets to functional genomics experiments to identify candidate cis-regulatory sequences. Given how essential these data have become, it is important that researchers using available datasets or performing their own genome-scale experiments understand the nature and limitations of echinoderm genomic analyses. In this chapter we highlight the current state of echinoderm genomic data and provide methodological considerations for common approaches, including analysis of transcriptome and functional genomics datasets.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Perfilação da Expressão Gênica / Genômica / Desenvolvimento Embrionário / Equinodermos Limite: Animals Idioma: En Revista: Methods Cell Biol Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Perfilação da Expressão Gênica / Genômica / Desenvolvimento Embrionário / Equinodermos Limite: Animals Idioma: En Revista: Methods Cell Biol Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos