Structural insight into the unique dsDNA binding topology of the human ORC2 wing helix domain.

Zhang, Jiahai; Guo, Qiong; Gao, Jun; Xu, Chao; Zhang, Beibei; Li, Mingwei; She, Jiaqi; Shi, Yunyu; Zhang, Zhiyong; Ruan, Ke; Wu, Jihui

Zhang, Jiahai; Guo, Qiong; Gao, Jun; Xu, Chao; Zhang, Beibei; Li, Mingwei; She, Jiaqi; Shi, Yunyu; Zhang, Zhiyong; Ruan, Ke; Wu, Jihui.

Afiliação

Zhang J; Hefei National Laboratory for Physical Sciences at the Microscale, School of Life Sciences, University of Science and Technology of China, Hefei, China.
Guo Q; Hefei National Laboratory for Physical Sciences at the Microscale, School of Life Sciences, University of Science and Technology of China, Hefei, China.
Gao J; Hefei National Laboratory for Physical Sciences at the Microscale, School of Life Sciences, University of Science and Technology of China, Hefei, China.
Xu C; Hefei National Laboratory for Physical Sciences at the Microscale, School of Life Sciences, University of Science and Technology of China, Hefei, China.
Zhang B; Hefei National Laboratory for Physical Sciences at the Microscale, School of Life Sciences, University of Science and Technology of China, Hefei, China.
Li M; Hefei National Laboratory for Physical Sciences at the Microscale, School of Life Sciences, University of Science and Technology of China, Hefei, China.
She J; Hefei National Laboratory for Physical Sciences at the Microscale, School of Life Sciences, University of Science and Technology of China, Hefei, China.
Shi Y; Hefei National Laboratory for Physical Sciences at the Microscale, School of Life Sciences, University of Science and Technology of China, Hefei, China.
Zhang Z; Hefei National Laboratory for Physical Sciences at the Microscale, School of Life Sciences, University of Science and Technology of China, Hefei, China.
Ruan K; Hefei National Laboratory for Physical Sciences at the Microscale, School of Life Sciences, University of Science and Technology of China, Hefei, China.
Wu J; Hefei National Laboratory for Physical Sciences at the Microscale, School of Life Sciences, University of Science and Technology of China, Hefei, China.

FEBS J ; 286(14): 2726-2736, 2019 07.

Article em En | MEDLINE | ID: mdl-30963726

Assuntos

DNA/química; Complexo de Reconhecimento de Origem/química; Sequência de Bases; Cristalização; Humanos; Espectroscopia de Ressonância Magnética; Domínios Proteicos; Estrutura Secundária de Proteína; Saccharomyces cerevisiae/genética

Palavras-chave

NMR; backbone dynamics; chemical shift assignment; molecular dynamics simulation; origin recognition complex subunit 2; wing helix domain

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: DNA / Complexo de Reconhecimento de Origem Limite: Humans Idioma: En Revista: FEBS J Assunto da revista: BIOQUIMICA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China País de publicação: Reino Unido

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