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Lineage-specific RUNX2 super-enhancer activates MYC and promotes the development of blastic plasmacytoid dendritic cell neoplasm.
Kubota, Sho; Tokunaga, Kenji; Umezu, Tomohiro; Yokomizo-Nakano, Takako; Sun, Yuqi; Oshima, Motohiko; Tan, Kar Tong; Yang, Henry; Kanai, Akinori; Iwanaga, Eisaku; Asou, Norio; Maeda, Takahiro; Nakagata, Naomi; Iwama, Atsushi; Ohyashiki, Kazuma; Osato, Motomi; Sashida, Goro.
Afiliação
  • Kubota S; Laboratory of Transcriptional Regulation in Leukemogenesis, International Research Center for Medical Sciences (IRCMS), Kumamoto University, 2-2-1 Honjo, Chuo Ward, Kumamoto, 860-0811, Japan.
  • Tokunaga K; Department of Hematology, Kumamoto University, 1-1-1 Honjo, Chuo Ward, Kumamoto, 860-8556, Japan.
  • Umezu T; Department of Hematology, Tokyo Medical University, 6-7-1 Nishi-Shinjuku, Shinjuku, Tokyo, 160-0023, Japan.
  • Yokomizo-Nakano T; Laboratory of Transcriptional Regulation in Leukemogenesis, International Research Center for Medical Sciences (IRCMS), Kumamoto University, 2-2-1 Honjo, Chuo Ward, Kumamoto, 860-0811, Japan.
  • Sun Y; Laboratory of Transcriptional Regulation in Leukemogenesis, International Research Center for Medical Sciences (IRCMS), Kumamoto University, 2-2-1 Honjo, Chuo Ward, Kumamoto, 860-0811, Japan.
  • Oshima M; Department of Cellular and Molecular Medicine, Chiba University, 1-8-1 Inohana, Chuo Ward, Chiba, 260-8670, Japan.
  • Tan KT; Division of Stem Cell and Molecular Medicine, Center for Stem Cell Biology and Regenerative Medicine, The Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato, Tokyo, 108-8639, Japan.
  • Yang H; Cancer Science Institute of Singapore, National University of Singapore, Singapore, 119077, Singapore.
  • Kanai A; Cancer Science Institute of Singapore, National University of Singapore, Singapore, 119077, Singapore.
  • Iwanaga E; Department of Molecular Oncology, Research Institute for Radiation Biology and Medicine, Hiroshima University, Hiroshima, 739-0046, Japan.
  • Asou N; Department of Hematology, Kumamoto University, 1-1-1 Honjo, Chuo Ward, Kumamoto, 860-8556, Japan.
  • Maeda T; Department of Hematology, International Medical Center, Saitama Medical University, Saitama, 350-1298, Japan.
  • Nakagata N; Department of General Medicine, Nagasaki University, Graduate School of Biomedical Science, Nagasaki, 852-8523, Japan.
  • Iwama A; Division of Reproductive Engineering, Center for Animal Resources and Development (CARD), Kumamoto University, 2-2-1 Honjo, Chuo Ward, Kumamoto, 860-0811, Japan.
  • Ohyashiki K; Department of Cellular and Molecular Medicine, Chiba University, 1-8-1 Inohana, Chuo Ward, Chiba, 260-8670, Japan.
  • Osato M; Division of Stem Cell and Molecular Medicine, Center for Stem Cell Biology and Regenerative Medicine, The Institute of Medical Science, The University of Tokyo, 4-6-1 Shirokanedai, Minato, Tokyo, 108-8639, Japan.
  • Sashida G; Department of Hematology, Tokyo Medical University, 6-7-1 Nishi-Shinjuku, Shinjuku, Tokyo, 160-0023, Japan.
Nat Commun ; 10(1): 1653, 2019 04 10.
Article em En | MEDLINE | ID: mdl-30971697
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células Dendríticas / Leucemia Mieloide Aguda / Proteínas Proto-Oncogênicas c-myc / Subunidade alfa 1 de Fator de Ligação ao Core Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Japão País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
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XML
PubMed Links
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Células Dendríticas / Leucemia Mieloide Aguda / Proteínas Proto-Oncogênicas c-myc / Subunidade alfa 1 de Fator de Ligação ao Core Tipo de estudo: Prognostic_studies Limite: Animals / Humans Idioma: En Revista: Nat Commun Assunto da revista: BIOLOGIA / CIENCIA Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Japão País de publicação: Reino Unido