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Quantitative Contribution of Six Major Transporters to the Hepatic Uptake of Drugs: "SLC-Phenotyping" Using Primary Human Hepatocytes.
Bi, Yi-An; Costales, Chester; Mathialagan, Sumathy; West, Mark; Eatemadpour, Soraya; Lazzaro, Sarah; Tylaska, Laurie; Scialis, Renato; Zhang, Hui; Umland, John; Kimoto, Emi; Tess, David A; Feng, Bo; Tremaine, Larry M; Varma, Manthena V S; Rodrigues, A David.
Afiliação
  • Bi YA; Medicine Design, Worldwide Research and Development, Pfizer Inc., Groton, Connecticut.
  • Costales C; Medicine Design, Worldwide Research and Development, Pfizer Inc., Groton, Connecticut.
  • Mathialagan S; Medicine Design, Worldwide Research and Development, Pfizer Inc., Groton, Connecticut.
  • West M; Medicine Design, Worldwide Research and Development, Pfizer Inc., Groton, Connecticut.
  • Eatemadpour S; Medicine Design, Worldwide Research and Development, Pfizer Inc., Groton, Connecticut.
  • Lazzaro S; Medicine Design, Worldwide Research and Development, Pfizer Inc., Groton, Connecticut.
  • Tylaska L; Medicine Design, Worldwide Research and Development, Pfizer Inc., Groton, Connecticut.
  • Scialis R; Medicine Design, Worldwide Research and Development, Pfizer Inc., Groton, Connecticut.
  • Zhang H; Medicine Design, Worldwide Research and Development, Pfizer Inc., Groton, Connecticut.
  • Umland J; Medicine Design, Worldwide Research and Development, Pfizer Inc., Groton, Connecticut.
  • Kimoto E; Medicine Design, Worldwide Research and Development, Pfizer Inc., Groton, Connecticut.
  • Tess DA; Medicine Design, Worldwide Research and Development, Pfizer Inc., Groton, Connecticut.
  • Feng B; Medicine Design, Worldwide Research and Development, Pfizer Inc., Groton, Connecticut.
  • Tremaine LM; Medicine Design, Worldwide Research and Development, Pfizer Inc., Groton, Connecticut.
  • Varma MVS; Medicine Design, Worldwide Research and Development, Pfizer Inc., Groton, Connecticut manthena.v.varma@pfizer.com.
  • Rodrigues AD; Medicine Design, Worldwide Research and Development, Pfizer Inc., Groton, Connecticut.
J Pharmacol Exp Ther ; 370(1): 72-83, 2019 07.
Article em En | MEDLINE | ID: mdl-30975793
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fenótipo / Preparações Farmacêuticas / Hepatócitos / Proteínas Carreadoras de Solutos / Fígado Limite: Humans Idioma: En Revista: J Pharmacol Exp Ther Ano de publicação: 2019 Tipo de documento: Article País de publicação: Estados Unidos
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Fenótipo / Preparações Farmacêuticas / Hepatócitos / Proteínas Carreadoras de Solutos / Fígado Limite: Humans Idioma: En Revista: J Pharmacol Exp Ther Ano de publicação: 2019 Tipo de documento: Article País de publicação: Estados Unidos