Structural and Functional Insights into Host Death Domains Inactivation by the Bacterial Arginine GlcNAcyltransferase Effector.

Ding, Jingjin; Pan, Xing; Du, Lijie; Yao, Qing; Xue, Juan; Yao, Hongwei; Wang, Da-Cheng; Li, Shan; Shao, Feng

Ding, Jingjin; Pan, Xing; Du, Lijie; Yao, Qing; Xue, Juan; Yao, Hongwei; Wang, Da-Cheng; Li, Shan; Shao, Feng.

Afiliação

Ding J; National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China; National Institute of Biological Sciences, Beijing 102206, China. Electronic address: jding@ibp.ac.cn.
Pan X; Bio-Medical Center, College of Life Science and Technology, Huazhong Agricultural University, Wuhan, Hubei 430070, China; Institute of Infection and Immunity, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei 442000, China.
Du L; Institute of Infection and Immunity, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei 442000, China.
Yao Q; National Institute of Biological Sciences, Beijing 102206, China.
Xue J; Institute of Infection and Immunity, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei 442000, China.
Yao H; College of Chemistry and Chemical Engineering, High-Field Nuclear Magnetic Resonance Center, Xiamen University, Xiamen, Fujian 361005, China.
Wang DC; National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China.
Li S; Bio-Medical Center, College of Life Science and Technology, Huazhong Agricultural University, Wuhan, Hubei 430070, China; Institute of Infection and Immunity, Taihe Hospital, Hubei University of Medicine, Shiyan, Hubei 442000, China. Electronic address: lishan@mail.hzau.edu.cn.
Shao F; National Institute of Biological Sciences, Beijing 102206, China; Tsinghua Institute of Multidisciplinary Biomedical Research, Tsinghua University, Beijing 102206, China. Electronic address: shaofeng@nibs.ac.cn.

Mol Cell ; 74(5): 922-935.e6, 2019 06 06.

Article em En | MEDLINE | ID: mdl-30979585

Assuntos

Escherichia coli Enteropatogênica/genética; Proteínas de Escherichia coli/química; Interações Hospedeiro-Patógeno/genética; Conformação Proteica; Fatores de Virulência/química; Animais; Apoptose/genética; Arginina/química; Arginina/genética; Coenzima A Ligases/química; Coenzima A Ligases/genética; Cristalografia por Raios X; Domínio de Morte/genética; Escherichia coli Enteropatogênica/patogenicidade; Proteínas de Escherichia coli/genética; Guanidina/química; Humanos; Manganês/química; Camundongos; Mutagênese; Proteína de Domínio de Morte Associada a Receptor de TNF/química; Proteína de Domínio de Morte Associada a Receptor de TNF/genética; Fatores de Virulência/genética

Palavras-chave

GlcNAcylation; arginine modification; bacteria-host interaction; bacterial virulence; death domain; death receptor signaling; glycosyltransferase; protein glycosylation; type III secretion system

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Conformação Proteica / Proteínas de Escherichia coli / Fatores de Virulência / Escherichia coli Enteropatogênica / Interações Hospedeiro-Patógeno Limite: Animals / Humans Idioma: En Revista: Mol Cell Assunto da revista: BIOLOGIA MOLECULAR Ano de publicação: 2019 Tipo de documento: Article País de publicação: Estados Unidos

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google