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Safety and efficacy of VRC01 broadly neutralising antibodies in adults with acutely treated HIV (RV397): a phase 2, randomised, double-blind, placebo-controlled trial.
Crowell, Trevor A; Colby, Donn J; Pinyakorn, Suteeraporn; Sacdalan, Carlo; Pagliuzza, Amélie; Intasan, Jintana; Benjapornpong, Khunthalee; Tangnaree, Kamonkan; Chomchey, Nitiya; Kroon, Eugène; de Souza, Mark S; Tovanabutra, Sodsai; Rolland, Morgane; Eller, Michael A; Paquin-Proulx, Dominic; Bolton, Diane L; Tokarev, Andrey; Thomas, Rasmi; Takata, Hiroshi; Trautmann, Lydie; Krebs, Shelly J; Modjarrad, Kayvon; McDermott, Adrian B; Bailer, Robert T; Doria-Rose, Nicole; Patel, Bijal; Gorelick, Robert J; Fullmer, Brandie A; Schuetz, Alexandra; Grandin, Pornsuk V; O'Connell, Robert J; Ledgerwood, Julie E; Graham, Barney S; Tressler, Randall; Mascola, John R; Chomont, Nicolas; Michael, Nelson L; Robb, Merlin L; Phanuphak, Nittaya; Ananworanich, Jintanat.
Afiliação
  • Crowell TA; US Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA; Henry M Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA. Electronic address: tcrowell@hivresearch.org.
  • Colby DJ; SEARCH, the Thai Red Cross AIDS Research Center, Bangkok, Thailand.
  • Pinyakorn S; US Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA; Henry M Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.
  • Sacdalan C; SEARCH, the Thai Red Cross AIDS Research Center, Bangkok, Thailand.
  • Pagliuzza A; Centre de Recherche du CHUM and Department of Microbiology, Infectiology and Immunology, Université de Montréal, Montreal, QC, Canada.
  • Intasan J; SEARCH, the Thai Red Cross AIDS Research Center, Bangkok, Thailand.
  • Benjapornpong K; SEARCH, the Thai Red Cross AIDS Research Center, Bangkok, Thailand.
  • Tangnaree K; SEARCH, the Thai Red Cross AIDS Research Center, Bangkok, Thailand.
  • Chomchey N; SEARCH, the Thai Red Cross AIDS Research Center, Bangkok, Thailand.
  • Kroon E; SEARCH, the Thai Red Cross AIDS Research Center, Bangkok, Thailand.
  • de Souza MS; Henry M Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA; SEARCH, the Thai Red Cross AIDS Research Center, Bangkok, Thailand.
  • Tovanabutra S; US Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA; Henry M Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.
  • Rolland M; US Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA; Henry M Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.
  • Eller MA; US Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA; Henry M Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.
  • Paquin-Proulx D; US Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA; Henry M Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.
  • Bolton DL; US Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA; Henry M Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.
  • Tokarev A; US Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA; Henry M Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.
  • Thomas R; US Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA; Henry M Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.
  • Takata H; US Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA; Henry M Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.
  • Trautmann L; US Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA; Henry M Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.
  • Krebs SJ; US Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA; Henry M Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.
  • Modjarrad K; US Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.
  • McDermott AB; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
  • Bailer RT; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
  • Doria-Rose N; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
  • Patel B; Division of AIDS, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
  • Gorelick RJ; AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USA.
  • Fullmer BA; AIDS and Cancer Virus Program, Frederick National Laboratory for Cancer Research, Frederick, MD, USA.
  • Schuetz A; US Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA; Henry M Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA; Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand.
  • Grandin PV; Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand.
  • O'Connell RJ; US Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA; Armed Forces Research Institute of Medical Sciences, Bangkok, Thailand.
  • Ledgerwood JE; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
  • Graham BS; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
  • Tressler R; Division of AIDS, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
  • Mascola JR; Vaccine Research Center, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
  • Chomont N; Centre de Recherche du CHUM and Department of Microbiology, Infectiology and Immunology, Université de Montréal, Montreal, QC, Canada.
  • Michael NL; US Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA.
  • Robb ML; US Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA; Henry M Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA.
  • Phanuphak N; SEARCH, the Thai Red Cross AIDS Research Center, Bangkok, Thailand.
  • Ananworanich J; US Military HIV Research Program, Walter Reed Army Institute of Research, Silver Spring, MD, USA; Henry M Jackson Foundation for the Advancement of Military Medicine, Bethesda, MD, USA; SEARCH, the Thai Red Cross AIDS Research Center, Bangkok, Thailand; Department of Global Health, University of Ams
Lancet HIV ; 6(5): e297-e306, 2019 05.
Article em En | MEDLINE | ID: mdl-31000477
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Anticorpos Anti-HIV / Infecções por HIV / HIV-1 / Anticorpos Amplamente Neutralizantes / Anticorpos Monoclonais Tipo de estudo: Clinical_trials Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Lancet HIV Ano de publicação: 2019 Tipo de documento: Article País de publicação: Holanda
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Anticorpos Anti-HIV / Infecções por HIV / HIV-1 / Anticorpos Amplamente Neutralizantes / Anticorpos Monoclonais Tipo de estudo: Clinical_trials Limite: Adult / Female / Humans / Male / Middle aged Idioma: En Revista: Lancet HIV Ano de publicação: 2019 Tipo de documento: Article País de publicação: Holanda