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Design, synthesis and biological evaluation of novel thioquinazolinone-based 2-aminobenzamide derivatives as potent histone deacetylase (HDAC) inhibitors.
Cheng, Chunhui; Yun, Fan; He, Jie; Ullah, Sadeeq; Yuan, Qipeng.
Afiliação
  • Cheng C; Key Laboratory of Biomedical Materials of Natural Macromolecules (Beijing University of Chemical Technology), Ministry of Education. College of Life Science and Technology, Beijing University of Chemical Technology, 15 Beisanhuan East Road, Beijing, 100029, China.
  • Yun F; Key Laboratory of Biomedical Materials of Natural Macromolecules (Beijing University of Chemical Technology), Ministry of Education. College of Life Science and Technology, Beijing University of Chemical Technology, 15 Beisanhuan East Road, Beijing, 100029, China.
  • He J; Key Laboratory of Biomedical Materials of Natural Macromolecules (Beijing University of Chemical Technology), Ministry of Education. College of Life Science and Technology, Beijing University of Chemical Technology, 15 Beisanhuan East Road, Beijing, 100029, China.
  • Ullah S; Key Laboratory of Biomedical Materials of Natural Macromolecules (Beijing University of Chemical Technology), Ministry of Education. College of Life Science and Technology, Beijing University of Chemical Technology, 15 Beisanhuan East Road, Beijing, 100029, China.
  • Yuan Q; Key Laboratory of Biomedical Materials of Natural Macromolecules (Beijing University of Chemical Technology), Ministry of Education. College of Life Science and Technology, Beijing University of Chemical Technology, 15 Beisanhuan East Road, Beijing, 100029, China. Electronic address: yuanqp@mail.buc
Eur J Med Chem ; 173: 185-202, 2019 Jul 01.
Article em En | MEDLINE | ID: mdl-31003060
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Desenho de Fármacos / Quinazolinonas / Inibidores de Histona Desacetilases / Ortoaminobenzoatos / Histona Desacetilases / Antineoplásicos Limite: Animals / Female / Humans Idioma: En Revista: Eur J Med Chem Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China País de publicação: França
Texto completo
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Desenho de Fármacos / Quinazolinonas / Inibidores de Histona Desacetilases / Ortoaminobenzoatos / Histona Desacetilases / Antineoplásicos Limite: Animals / Female / Humans Idioma: En Revista: Eur J Med Chem Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China País de publicação: França