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U2AF1 mutations induce oncogenic IRAK4 isoforms and activate innate immune pathways in myeloid malignancies.
Smith, Molly A; Choudhary, Gaurav S; Pellagatti, Andrea; Choi, Kwangmin; Bolanos, Lyndsey C; Bhagat, Tushar D; Gordon-Mitchell, Shanisha; Von Ahrens, Dagny; Pradhan, Kith; Steeples, Violetta; Kim, Sanghyun; Steidl, Ulrich; Walter, Matthew; Fraser, Iain D C; Kulkarni, Aishwarya; Salomonis, Nathan; Komurov, Kakajan; Boultwood, Jacqueline; Verma, Amit; Starczynowski, Daniel T.
Afiliação
  • Smith MA; Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
  • Choudhary GS; Department of Cancer Biology, University of Cincinnati, Cincinnati, OH, USA.
  • Pellagatti A; Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY, USA.
  • Choi K; Nuffield Division of Clinical Laboratory Sciences, Radcliffe Department of Medicine, University of Oxford and Oxford BRC Haematology Theme, Oxford, UK.
  • Bolanos LC; Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
  • Bhagat TD; Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
  • Gordon-Mitchell S; Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY, USA.
  • Von Ahrens D; Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY, USA.
  • Pradhan K; Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY, USA.
  • Steeples V; Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY, USA.
  • Kim S; Nuffield Division of Clinical Laboratory Sciences, Radcliffe Department of Medicine, University of Oxford and Oxford BRC Haematology Theme, Oxford, UK.
  • Steidl U; Department of Medicine, Washington University, St. Louis, MO, USA.
  • Walter M; Albert Einstein College of Medicine, Montefiore Medical Center, Bronx, NY, USA.
  • Fraser IDC; Department of Medicine, Washington University, St. Louis, MO, USA.
  • Kulkarni A; Laboratory of Immune System Biology, National Institute of Allergy and Infectious Diseases, National Institute of Health, Bethesda, MD, USA.
  • Salomonis N; Department of Electrical Engineering and Computer Science, University of Cincinnati, Cincinnati, OH, USA.
  • Komurov K; Division of Biomedical Informatics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
  • Boultwood J; Department of Pediatrics, University of Cincinnati, Cincinnati, OH, USA.
  • Verma A; Division of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, USA.
  • Starczynowski DT; Department of Pediatrics, University of Cincinnati, Cincinnati, OH, USA.
Nat Cell Biol ; 21(5): 640-650, 2019 05.
Article em En | MEDLINE | ID: mdl-31011167
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Síndromes Mielodisplásicas / Leucemia Mieloide Aguda / Quinases Associadas a Receptores de Interleucina-1 / Fator de Processamento U2AF Tipo de estudo: Prognostic_studies Limite: Female / Humans / Male Idioma: En Revista: Nat Cell Biol Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido
Texto completo
Adicionar na Minha BVS
Imprimir
XML
PubMed Links
Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Síndromes Mielodisplásicas / Leucemia Mieloide Aguda / Quinases Associadas a Receptores de Interleucina-1 / Fator de Processamento U2AF Tipo de estudo: Prognostic_studies Limite: Female / Humans / Male Idioma: En Revista: Nat Cell Biol Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Estados Unidos País de publicação: Reino Unido