Drug repurposing in oncology: Compounds, pathways, phenotypes and computational approaches for colorectal cancer.

Nowak-Sliwinska, Patrycja; Scapozza, Leonardo; Ruiz i Altaba, Ariel

Nowak-Sliwinska, Patrycja; Scapozza, Leonardo; Ruiz i Altaba, Ariel.

Afiliação

Nowak-Sliwinska P; School of Pharmaceutical Sciences, University of Geneva and University of Lausanne, Geneva, Switzerland; Translational Research Center in Oncohaematology, University of Geneva, Rue Michel Servet 1, 1211 Geneva 4, Switzerland. Electronic address: Patrycja.Nowak-Sliwinska@unige.ch.
Scapozza L; School of Pharmaceutical Sciences, University of Geneva and University of Lausanne, Geneva, Switzerland.
Ruiz i Altaba A; Department of Genetic Medicine and Development, Faculty of Medicine, University of Geneva, Rue Michel Servet 1, 1211 Geneva 4, Switzerland.

Biochim Biophys Acta Rev Cancer ; 1871(2): 434-454, 2019 04.

Article em En | MEDLINE | ID: mdl-31034926

Assuntos

Antineoplásicos/farmacologia; Neoplasias Colorretais/tratamento farmacológico; Reposicionamento de Medicamentos/métodos; Aprendizado de Máquina; Animais; Humanos; Oncologia/métodos; Fenótipo

Palavras-chave

Colorectal cancer; Computational approaches; Drug repositioning; Mechanism of action; Omics; On/off-target effects; Phenotypes; Polypharmacology; Repurposing in oncology; Side effects; Signaling pathways

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Neoplasias Colorretais / Reposicionamento de Medicamentos / Aprendizado de Máquina / Antineoplásicos Limite: Animals / Humans Idioma: En Revista: Biochim Biophys Acta Rev Cancer Ano de publicação: 2019 Tipo de documento: Article País de publicação: Holanda

Texto completo

Adicionar na Minha BVS

Imprimir

XML

PubMed Links

Buscar no Google