NLRX1 Enhances Glutamate Uptake and Inhibits Glutamate Release by Astrocytes.

Mahmoud, Shaimaa; Gharagozloo, Marjan; Simard, Camille; Amrani, Abdelaziz; Gris, Denis

Mahmoud, Shaimaa; Gharagozloo, Marjan; Simard, Camille; Amrani, Abdelaziz; Gris, Denis.

Afiliação

Mahmoud S; Program of Immunology, Department of Pharmacology-Physiology, Faculty of Medicine and Health Sciences, University of Sherbrooke, Sherbrooke, QC J1H 5N4, Canada. Shaimaa.Mahmoud@usherbooke.ca.
Gharagozloo M; Program of Immunology, Department of Pharmacology-Physiology, Faculty of Medicine and Health Sciences, University of Sherbrooke, Sherbrooke, QC J1H 5N4, Canada. Marjan.Gharagozloo@usherbrooke.ca.
Simard C; Program of Immunology, Department of Pharmacology-Physiology, Faculty of Medicine and Health Sciences, University of Sherbrooke, Sherbrooke, QC J1H 5N4, Canada. Camille.Simard@usherbrooke.ca.
Amrani A; Program of Immunology, Department of Pediatrics, CR-CHUS, Faculty of Medicine and Health Sciences, University of Sherbrooke, Sherbrooke, QC J1H 5N4, Canada. Abdelaziz.Amrani@usherbrooke.ca.
Gris D; Program of Immunology, Department of Pharmacology-Physiology, Faculty of Medicine and Health Sciences, University of Sherbrooke, Sherbrooke, QC J1H 5N4, Canada. Denis.Gris@usherbrooke.ca.

Cells ; 8(5)2019 04 30.

Article em En | MEDLINE | ID: mdl-31052241

Assuntos

Astrócitos/metabolismo; Ácido Glutâmico/metabolismo; Mitocôndrias/metabolismo; Proteínas Mitocondriais/fisiologia; Animais; Astrócitos/citologia; Transporte Biológico; Células Cultivadas; Sistema Nervoso Central/metabolismo; Proteínas de Transporte de Glutamato da Membrana Plasmática/fisiologia; Homeostase; Camundongos; Camundongos Endogâmicos C57BL; Camundongos Endogâmicos NOD

Palavras-chave

CNS; NLRX1; astrocytes; excitotoxicity; glutamate release; glutamate uptake

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Astrócitos / Ácido Glutâmico / Proteínas Mitocondriais / Mitocôndrias Limite: Animals Idioma: En Revista: Cells Ano de publicação: 2019 Tipo de documento: Article País de afiliação: Canadá

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