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Medications for pain relief in outpatient endometrial sampling or biopsy: a systematic review and network meta-analysis.
Abbas, Ahmed M; Samy, Ahmed; El-Naser Abd El-Gaber Ali, Abd; Khodry, Mustafa M; Ahmed, Mohammad A M; El-Rasheedy, Mahmoud I; Abdallah, Khaled M; Mohammed, Abd-Elhalim; Abdelbaky, Waleed H; Raslan, Osama Kamal; Badawy, Mahmoud A; Elktatny, Hossam H.
Afiliação
  • Abbas AM; Department of Obstetrics and Gynecology, Faculty of Medicine, Assiut University, Assiut, Egypt. Electronic address: ahmedabbas@aun.edu.eg.
  • Samy A; Department of Obstetrics and Gynecology, Faculty of Medicine, Cairo University, Cairo, Egypt.
  • El-Naser Abd El-Gaber Ali A; Department of Obstetrics and Gynecology, Faculty of Medicine, South Valley University, Qena, Egypt.
  • Khodry MM; Department of Obstetrics and Gynecology, Faculty of Medicine, South Valley University, Qena, Egypt.
  • Ahmed MAM; Department of Obstetrics and Gynecology, Faculty of Medicine, South Valley University, Qena, Egypt.
  • El-Rasheedy MI; Department of Obstetrics and Gynecology, Faculty of Medicine, Al-Azhar University, Assiut, Egypt.
  • Abdallah KM; Department of Obstetrics and Gynecology, Faculty of Medicine, Al-Azhar University, Assiut, Egypt.
  • Mohammed AE; Department of Obstetrics and Gynecology, Faculty of Medicine, Al-Azhar University, Assiut, Egypt.
  • Abdelbaky WH; Department of Obstetrics and Gynecology, Faculty of Medicine, Al-Azhar University, Assiut, Egypt.
  • Raslan OK; Department of Obstetrics and Gynecology, Faculty of Medicine, Al-Azhar University, Assiut, Egypt.
  • Badawy MA; Department of Obstetrics and Gynecology, Faculty of Medicine, Al-Azhar University, Assiut, Egypt.
  • Elktatny HH; Department of Obstetrics and Gynecology, Faculty of Medicine, Al-Azhar University, Assiut, Egypt.
Fertil Steril ; 112(1): 140-148.e12, 2019 07.
Article em En | MEDLINE | ID: mdl-31056314
OBJECTIVE: To determine the most effective analgesia for pain relief during the outpatient endometrial biopsy (OEB) or outpatient hysteroscopy with endometrial aspiration (EA). DESIGN: Systematic review and network meta-analysis of randomized controlled trials. SETTING: Not applicable. PATIENT(S): Pre- or postmenopausal women undergoing OEB or outpatient hysteroscopy with EA for evaluation of uterine pathology. INTERVENTION(S): We conducted an electronic search of the following bibliographic databases: Medline via PubMed, SCOPUS, Web of Science, ClinicalTrials.gov, and Cochrane Central Register of Controlled Trials (CENTRAL). MAIN OUTCOME MEASURE(S): The intensity of pain during, immediately after, and 10-30 minutes after procedure assessed by the 10-cm visual analog scale. RESULT(S): Lidocaine spray was the most effective medication for reducing pain during OEB (P-score = 0.83) and immediately after OEB (P-score = 0.96). On the other hand, naproxen sodium was the most effective medication for reducing pain during outpatient hysteroscopy with EA (P-score = 1.00), followed by misoprostol plus lidocaine (P-score = 0.87). CONCLUSION(S): Lidocaine spray, either alone or with topical application of lidocaine, is the most effective medication for reducing the pain during and after the OEB. Naproxen sodium is the most effective analgesic option during outpatient hysteroscopy with EA.
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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dor / Hemorragia Uterina / Biópsia / Histeroscopia / Endométrio / Manejo da Dor / Assistência Ambulatorial / Analgésicos Tipo de estudo: Clinical_trials / Diagnostic_studies / Etiology_studies / Systematic_reviews Limite: Female / Humans Idioma: En Revista: Fertil Steril Ano de publicação: 2019 Tipo de documento: Article País de publicação: Estados Unidos

Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Dor / Hemorragia Uterina / Biópsia / Histeroscopia / Endométrio / Manejo da Dor / Assistência Ambulatorial / Analgésicos Tipo de estudo: Clinical_trials / Diagnostic_studies / Etiology_studies / Systematic_reviews Limite: Female / Humans Idioma: En Revista: Fertil Steril Ano de publicação: 2019 Tipo de documento: Article País de publicação: Estados Unidos