Recombinant Treponema pallidum protein Tp47 promotes the migration and adherence of THP-1â¯cells to human dermal vascular smooth muscle cells by inducing MCP-1 and ICAM-1 expression.

Gao, Zheng-Xiang; Liu, Dan; Liu, Li-Li; Lin, Li-Rong; Tong, Man-Li; Niu, Jian-Jun; Yang, Tian-Ci

Recombinant Treponema pallidum protein Tp47 promotes the migration and adherence of THP-1â¯cells to human dermal vascular smooth muscle cells by inducing MCP-1 and ICAM-1 expression.

Gao, Zheng-Xiang; Liu, Dan; Liu, Li-Li; Lin, Li-Rong; Tong, Man-Li; Niu, Jian-Jun; Yang, Tian-Ci.

Afiliação

Gao ZX; Center of Clinical Laboratory, Zhongshan Hospital, School of Medicine, Xiamen University, Xiamen, 361004, China; Institute of Infectious Disease, School of Medicine, Xiamen University, Xiamen, 361004, China.
Liu D; Center of Clinical Laboratory, Zhongshan Hospital, School of Medicine, Xiamen University, Xiamen, 361004, China.
Liu LL; Center of Clinical Laboratory, Zhongshan Hospital, School of Medicine, Xiamen University, Xiamen, 361004, China; Institute of Infectious Disease, School of Medicine, Xiamen University, Xiamen, 361004, China.
Lin LR; Center of Clinical Laboratory, Zhongshan Hospital, School of Medicine, Xiamen University, Xiamen, 361004, China; Institute of Infectious Disease, School of Medicine, Xiamen University, Xiamen, 361004, China.
Tong ML; Center of Clinical Laboratory, Zhongshan Hospital, School of Medicine, Xiamen University, Xiamen, 361004, China.
Niu JJ; Center of Clinical Laboratory, Zhongshan Hospital, School of Medicine, Xiamen University, Xiamen, 361004, China; Institute of Infectious Disease, School of Medicine, Xiamen University, Xiamen, 361004, China. Electronic address: niujianjun211@xmu.edu.cn.
Yang TC; Center of Clinical Laboratory, Zhongshan Hospital, School of Medicine, Xiamen University, Xiamen, 361004, China; Institute of Infectious Disease, School of Medicine, Xiamen University, Xiamen, 361004, China. Electronic address: yangtianci@xmu.edu.cn.

Exp Cell Res ; 381(1): 150-162, 2019 08 01.

Article em En | MEDLINE | ID: mdl-31075255

Assuntos

Músculo Liso Vascular/metabolismo; Sífilis/microbiologia; Treponema pallidum/fisiologia; beta-Lactamases/fisiologia; Adesão Celular; Movimento Celular; Células Cultivadas; Quimiocina CCL2/metabolismo; Derme/metabolismo; Derme/patologia; Humanos; Molécula 1 de Adesão Intercelular/metabolismo; Músculo Liso Vascular/patologia; NF-kappa B/metabolismo; Fosforilação; Proteínas Proto-Oncogênicas c-akt/metabolismo; Proteínas Recombinantes; Transdução de Sinais; Sífilis/metabolismo; Sífilis/patologia; Células THP-1; beta-Lactamases/genética; Proteínas Quinases p38 Ativadas por Mitógeno/metabolismo

Palavras-chave

Chemoattractant protein-1; Human dermal vascular smooth muscle cells; Intercellular adhesion molecule-1; THP-1â¯cells; Treponema pallidum

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Texto completo: 1 Coleções: 01-internacional Base de dados: MEDLINE Assunto principal: Treponema pallidum / Beta-Lactamases / Sífilis / Músculo Liso Vascular Limite: Humans Idioma: En Revista: Exp Cell Res Ano de publicação: 2019 Tipo de documento: Article País de afiliação: China País de publicação: Estados Unidos

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